Department of Anesthesiology

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Publications

Author Title [ Type(Asc)] Year
Filters: Author is Hemmings, Hugh C  [Clear All Filters]
Journal Article
Hemmings HC.  2007.  Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor.. Anesthesiology. 107(5):694-6.
Eger EI, Raines DE, Shafer SL, Hemmings HC, Sonner JM.  2008.  Is a new paradigm needed to explain how inhaled anesthetics produce immobility? Anesth Analg. 107(3):832-48.
Perouansky M, Hemmings HC.  2009.  Neurotoxicity of general anesthetics: cause for concern? Anesthesiology. 111(6):1365-71.
Hemmings HC.  2004.  Neuroprotection by Na+ channel blockade.. J Neurosurg Anesthesiol. 16(1):100-1.
Ouyang W, Hemmings HC.  2007.  Isoform-selective effects of isoflurane on voltage-gated Na+ channels.. Anesthesiology. 107(1):91-8.
Platholi J, Herold KF, Hemmings HC, Halpain S.  2014.  Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.. PLoS One. 9(7):e102978.
Zhao W, Zhang M, Liu J, Liang P, Wang R, Hemmings HC, Zhou C.  2019.  Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.. Anesthesiology. 131(1):94-104.
Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC.  2017.  Isoflurane modulates activation and inactivation gating of the prokaryotic Na(+) channel NaChBac.. J Gen Physiol. 149(6):623-638.
Herold KF, Nau C, Ouyang W, Hemmings HC.  2009.  Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.. Anesthesiology. 111(3):591-9.
Baumgart JP, Zhou Z-Y, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC.  2015.  Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.. Proc Natl Acad Sci U S A. 112(38):11959-64.
Ouyang W, Jih T-Y, Zhang T-T, Correa AM, Hemmings HC.  2007.  Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.. J Pharmacol Exp Ther. 322(3):1076-83.
Torturo CL, Zhou Z-Y, Ryan TA, Hemmings HC.  2019.  Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons.. eNeuro. 6(1)
Ouyang W, Wang G, Hemmings HC.  2003.  Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.. Mol Pharmacol. 64(2):373-81.
Zhang Y, Sharma M, Eger EI, Laster MJ, Hemmings HC, R Harris A.  2008.  Intrathecal veratridine administration increases minimum alveolar concentration in rats.. Anesth Analg. 107(3):875-8.
Pryor KO, Hemmings HC.  2013.  Increased Risk of Awareness under Anesthesia: An Issue of Consciousness or of Memory? Anesthesiology.
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.
Snyder GL, Galdi S, Hendrick JP, Hemmings HC.  2007.  General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.. Neuropharmacology. 53(5):619-30.
Pashkov VN, Westphalen RI, Hemmings HC.  2002.  General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals.. Anesthesiology. 97(6):1500-6.
Hemmings HC, Yan W, Westphalen RI, Ryan TA.  2005.  The general anesthetic isoflurane depresses synaptic vesicle exocytosis.. Mol Pharmacol. 67(5):1591-9.
Shahani SK, Lingamaneni R, Hemmings HC.  2002.  General anesthetic actions on norepinephrine, dopamine, and gamma-aminobutyric acid transporters in stably transfected cells.. Anesth Analg. 95(4):893-9,tableofcontents.
Hemmings HC, Flood P.  2008.  Galloping in full pursuit of the mechanism of anesthetic immobility.. Anesthesiology. 108(6):975-6.
Albert KA, Hemmings HC, Adamo AIB, Potkin SG, Akbarian S, Sandman CA, Cotman CW, Bunney WE, Greengard P.  2002.  Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia.. Arch Gen Psychiatry. 59(8):705-12.
Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL.  2005.  Emerging molecular mechanisms of general anesthetic action.. Trends Pharmacol Sci. 26(10):503-10.
Westphalen RI, Hemmings HC.  2003.  Effects of isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals.. Anesthesiology. 98(2):364-72.
Pashkov VN, Hemmings HC.  2002.  The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals.. Anesth Analg. 95(5):1274-81,tableofcontents.