Selected academic research
De Barros V, Niemela G, Rubin J, Lee EM, Jotwani RM. CASSIE: A Specialized AI Conversational Agent for Chronic Pelvic Pain Management [ID 3638]. Obstetrics & Gynecology. 2026 May 1;147(5S):11S.
Kumar P, Siddarthan I, Keim CK, Cho DK, Rubin JE, White RS, Jotwani R. Integrating AI Segmentation, Simulated Digital Twins, and Extended Reality into Medical Education: A Narrative Technical Review and Proof-of-Concept Case Study. Journal of Personalized Medicine. 2026 Apr 3;16(4):202.
Henry O, Brumberger E, Jotwani R, Sigaras A, Sriram S, Yeh IM, Rubin J. Using an Artificial Intelligence Conversational Agent in Virtual Reality to Teach Serious Illness Communication Skills to Residents. Journal of Graduate Medical Education. 2026 Apr 1;18(2):193-4.
Kim J, Lui B, Goldstein PA, Rubin JE, White RS, Jotwani R. From Data to Decisions: Harnessing Multi-Agent Systems for Safer, Smarter, and More Personalized Perioperative Care. Journal of Personalized Medicine. 2025 Nov 6;15(11):540.
Rizzo A, Mozgai S, Sigaras A, Rubin JE, Jotwani R. Expert Consensus Best Practices for the Safe, Ethical, and Effective Design and Implementation of Artificially Intelligent Conversational Agent (ie, Chatbot/Virtual Human) Systems in Health Care Applications. Journal of Medical Extended Reality. 2025 Sep 8;2(1):29941520251369450.
Rubin JE, Jotwani R. Curriculum for neuraxial procedural training using medical extended reality. British Journal of Anaesthesia. 2025 Jun 1;134(6):1797-800.
Siddarthan IJ, Huang C, Kumar P, Rubin JE, White RS, Mehta N, Jotwani R. Virtual Reality for Pre-Procedural Planning of Interventional Pain Procedures: A Real-World Application Case Series. Journal of Clinical Medicine. 2025 Apr 27;14(9):3019.
Jumreornvong O, Chang D, Galdo GP, Yong J, Jotwani R. Artificial intelligence assisted virtual reality training module for Gasserian ganglion block. Interv Pain Med. 2025 Jan 6;4(1):100536.
Kim, Richard W. DO, MBA; Chitneni, Ahish DO; Rubin, John Edwin MD; White, Robert MD; Jotwani, Rohan MD, MBA. Virtual Reality Therapy for Chronic Pain: A Scoping Review on Indications, Mechanisms of Action, and Effectiveness. Topics in Pain Management 40(5):p 1-9, December 2024.
Cho D, Berman A, Rubin JE, and Jotwani R. (2024) Perceptions and attitudes on medical education extended reality applications from a Single Anesthesiology Residency Program, Journal of Medical Extended Reality 1:1, 174–178.
Cho JS, Thaker DM, Jotwani R, Hao D. Extended Reality for Neuraxial Procedures: A Scoping Review. J Med Ext Real. Epub 2024 Jul 3.
Cho JS, Jotwani R, Chan S, Thaker DM, On JD, Yong RJ, Hao D. Extended reality navigation for pain procedures: a narrative review. Reg Anesth Pain Med. 2024 May 16:rapm-2024-105352. Epub ahead of print.
Rubin JE, Shanker A, Berman AB, Pandian B, Jotwani R. Utilisation of extended reality for preprocedural planning and education in anaesthesiology: a practical guide for spatial computing. Br J Anaesth. 2024 Apr 11:S0007-0912(24)00139-9. Epub ahead of print.
Spiegel BMR, Rizzo A, Persky S, Liran O, Wiederhold B, Woods S, Donovan K, Sarkar K, Xiang H, Joo S, Jotwani R, Lang M, Paul M, Senter-Zapata M, Widmeier K, Zhang H. What Is Medical Extended Reality? A Taxonomy Defining the Current Breadth and Depth of an Evolving Field. J Med Ext Real. 2024 Jan 1;1(1):4-12. Epub 2024 Jan 25.
Rubin JE, Pandian B, Jotwani R, Pryor KO, Rubin LA, Mack PF. Leveraging spatial computing to improve crisis management training in anesthesiology. J Clin Anesth. 2023 Dec 16;93:111358.
Rubin JE, White RS, Boyer RB, Jotwani R. Obstetric anesthesiology and extended reality: an introduction to future uses of spatial computing in obstetric anesthesiology. Int J Obstet Anesth. 2023 Nov 20:103959.
Wang EF, Jotwani R. Virtual reality therapy for myofascial pain: Evolving towards an evidence-based non- pharmacologic adjuvant intervention. Interventional Pain Medicine. 2023 Mar 1;2(1):100181.
Wang EF, Yu J, Rubin JE, Jotwani R. Virtual reality training and modeling to aid in pre-procedural practice for thoracic nerve root block in the setting of a schwannoma. Interventional Pain Medicine. 2023 Mar 1;2(1):100180.
Jotwani R, Fiore M, Yong RJ, Hao D. Virtual reality for procedural education: Lumbar medial branch radiofrequency neurotomy. Interventional Pain Medicine. 2021 Dec 1;1(1):100088.
