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Department of Anesthesiology
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Journal Article
Tibbs GR, Posson DJ, Goldstein PA.  2016.  Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain? Trends Pharmacol Sci. 37(7):522-42.
Hemmings HC, Riegelhaupt PM, Kelz MB, Solt K, Eckenhoff RG, Orser BA, Goldstein PA.  2019.  Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery.. Trends Pharmacol Sci. 40(7):464-481.
Jia F, Yue M, Chandra D, Keramidas A, Goldstein PA, Homanics GE, Harrison NL.  2008.  Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus.. J Neurosci. 28(1):106-15.
Roepke TK, Kontogeorgis A, Ovanez C, Xu X, Young JB, Purtell K, Goldstein PA, Christini DJ, Peters NS, Akar FG et al..  2008.  Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).. FASEB J. 22(10):3648-60.
Ying S-W, Kanda VA, Hu Z, Purtell K, King EC, Abbott GW, Goldstein PA.  2012.  Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.. PLoS One. 7(8):e42756.
Pryor KO, Fahey TJ, Lien CA, Goldstein PA.  2004.  Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population: a randomized controlled trial.. JAMA. 291(1):79-87.
Pryor KO, Lien CA, Fahey TJ, Goldstein PA.  2006.  Supplemental oxygen and risk of surgical wound infection.. JAMA. 295(14):1642;authorreply1642-3.
Safavynia SA, Goldstein PA.  2018.  The Role of Neuroinflammation in Postoperative Cognitive Dysfunction: Moving From Hypothesis to Treatment.. Front Psychiatry. 9:752.
Calder EL, Tchieu J, Steinbeck JA, Tu E, Keros S, Ying S-W, Jaiswal MK, Cornacchia D, Goldstein PA, Tabar V et al..  2015.  Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation.. J Neurosci. 35(33):11462-81.
Riegelhaupt PM, Hemmings HC, Goldstein PA.  2016.  Relevance of Clinical Relevance.. Anesthesiology. 125(4):821-2.
Heuermann RJ, Jaramillo TC, Ying S-W, Suter BA, Lyman KA, Han Y, Lewis AS, Hampton TG, Shepherd GMG, Goldstein PA et al..  2016.  Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy.. Neurobiol Dis. 85:81-92.
Jaiswal MK, Keros S, Zhao M, Inan M, Schwartz TH, Anderson SA, Homanics GE, Goldstein PA.  2015.  Reduction in focal ictal activity following transplantation of MGE interneurons requires expression of the GABAA receptor α4 subunit.. Front Cell Neurosci. 9:127.
Evered LA, Goldstein PA.  2021.  Reducing Perioperative Neurocognitive Disorders (PND) Through Depth of Anesthesia Monitoring: A Critical Review.. Int J Gen Med. 14:153-162.
Cooke FE, Samuels JD, Pomp A, Gadalla F, Wu X, Afaneh C, Dakin GF, Goldstein PA.  2018.  A Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Acetaminophen on Hospital Length of Stay in Obese Individuals Undergoing Sleeve Gastrectomy.. Obes Surg.
Ying S-W, Goldstein PA.  2005.  Propofol-block of SK channels in reticular thalamic neurons enhances GABAergic inhibition in relay neurons.. J Neurophysiol. 93(4):1935-48.
Ying S-W, Goldstein PA.  2005.  Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA(A) receptor chloride channels.. Mol Pain. 1:2.
Ying S-W, Abbas SY, Harrison NL, Goldstein PA.  2006.  Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons.. Eur J Neurosci. 23(2):465-80.
Goldstein PA, Elsen FP, Ying S-W, Ferguson C, Homanics GE, Harrison NL.  2002.  Prolongation of hippocampal miniature inhibitory postsynaptic currents in mice lacking the GABA(A) receptor alpha1 subunit.. J Neurophysiol. 88(6):3208-17.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
Bustillo MA, Lien CA, Mack PFogarty, Kopman DJ, Safavynia SA, Rubin L, Stein D, Härtl R, Stieg PE, R Hernandez N et al..  2018.  Optimizing patient access during an emergency while using intraoperative computed tomography.. World Neurosurg.
Memtsoudis SG, Ivascu NS, Pryor KO, Goldstein PA.  2020.  Obesity as a risk factor for poor outcome in COVID-19-induced lung injury: the potential role of undiagnosed obstructive sleep apnoea.. Br J Anaesth.
Goldstein PA.  2018.  Nonhuman Primates in Anesthesia Research: Have We Reached the End of the Road? Anesth Analg. 126(6):2129-2134.
Cook DC, Goldstein PA.  2021.  Non-canonical molecular targets for novel analgesics: Intracellular calcium and HCN channels.. Curr Neuropharmacol.
Tchieu J, Calder EL, Guttikonda SR, Gutzwiller EM, Aromolaran KA, Steinbeck JA, Goldstein PA, Studer L.  2019.  NFIA is a gliogenic switch enabling rapid derivation of functional human astrocytes from pluripotent stem cells.. Nat Biotechnol.
Grosland JO, Todd MM, Goldstein PA.  2018.  Neuromonitoring in the ambulatory anesthesia setting: a pro-con discussion.. Curr Opin Anaesthesiol.