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Department of Anesthesiology
Author Title [ Type(Asc)] Year
Filters: Author is Tibbs, Gareth R  [Clear All Filters]
Journal Article
Tibbs GR, Posson DJ, Goldstein PA.  2016.  Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain? Trends Pharmacol Sci. 37(7):522-42.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
Cacheaux LP, Topf N, Tibbs GR, Schaefer UR, Levi R, Harrison NL, Abbott GW, Goldstein PA.  2005.  Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.. J Pharmacol Exp Ther. 315(2):517-25.
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.
Riegelhaupt PM, Tibbs GR, Goldstein PA.  2018.  HCN and K Channels in Anesthetic Mechanisms Research.. Methods Enzymol. 602:391-416.
Lyashchenko AK, Redd KJ, Goldstein PA, Tibbs GR.  2014.  cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.. PLoS One. 9(7):e101236.
Joyce RL, Beyer NP, Vasilopoulos G, Woll K, Hall AC, Eckenhoff RG, Barman DN, J Warren D, Tibbs GR, Goldstein PA.  2019.  Alkylphenol inverse agonists of HCN1 gating: H-bond propensity, ring saturation and adduct geometry differentially determine efficacy and potency.. Biochem Pharmacol.