Department of Anesthesiology
Author Title Type [ Year(Desc)]
Filters: Author is Nimigean, Crina M  [Clear All Filters]
2018
Kowal J, Biyani N, Chami M, Scherer S, Rzepiela AJ, Baumgartner P, Upadhyay V, Nimigean CM, Stahlberg H.  2018.  High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.. Structure. 26(1):20-27.e3.
Schmidpeter PAM, Gao X, Uphadyay V, Rheinberger J, Nimigean CM.  2018.  Ligand binding and activation properties of the purified bacterial cyclic nucleotide-gated channel SthK.. J Gen Physiol.
Rheinberger J, Gao X, Schmidpeter PAm, Nimigean CM.  2018.  Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.. Elife. 7
Posson DJ, Rusinova R, Andersen OS, Nimigean CM.  2018.  Stopped-Flow Fluorometric Ion Flux Assay for Ligand-Gated Ion Channel Studies.. Methods Mol Biol. 1684:223-235.
2019
Xu Y, Zhang D, Rogawski R, Nimigean CM, McDermott AE.  2019.  Identifying coupled clusters of allostery participants through chemical shift perturbations.. Proc Natl Acad Sci U S A. 116(6):2078-2085.
2020
Fan C, Sukomon N, Flood E, Rheinberger J, Allen TW, Nimigean CM.  2020.  Ball-and-chain inactivation in a calcium-gated potassium channel.. Nature. 580(7802):288-293.
Wague A, Joseph TT, Woll KA, Bu W, Vaidya KA, Bhanu NV, Garcia BA, Nimigean CM, Eckenhoff RG, Riegelhaupt PM.  2020.  Mechanistic insights into volatile anesthetic modulation of K2P channels.. Elife. 9
Nimigean CM.  2020.  Polyamine block of MthK potassium channels.. J Gen Physiol. 152(7)
2021
Schmidpeter PAM, Nimigean CM.  2021.  Correlating ion channel structure and function.. Methods Enzymol. 652:3-30.
2022
Nimigean CM.  2022.  35 years of channelling potassium ions.. Nature. 608(7924):670-672.
Schmidpeter PAM, Wu D, Rheinberger J, Riegelhaupt PM, Tang H, Robinson CV, Nimigean CM.  2022.  Anionic lipids unlock the gates of select ion channels in the pacemaker family.. Nat Struct Mol Biol. 29(11):1092-1100.
Sukomon N, Fan C, Nimigean CM.  2022.  Ball-and-Chain Inactivation in Potassium Channels.. Annu Rev Biophys.
Gao X, Schmidpeter PAM, Berka V, Durham RJ, Fan C, Jayaraman V, Nimigean CM.  2022.  Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.. Nat Commun. 13(1):6919.
2023
Fan C, Flood E, Sukomon N, Agarwal S, Allen TW, Nimigean CM.  2023.  Calcium-gated potassium channel blockade via membrane-facing fenestrations.. Nat Chem Biol.
Pan Y, Pohjolainen E, Schmidpeter PAM, Vaiana AC, Nimigean CM, Grubmüller H, Scheuring S.  2023.  Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel.. Nat Struct Mol Biol. 30(4):512-520.
Schmidpeter PAM, Petroff JT, Khajoueinejad L, Wague A, Frankfater C, Cheng WWL, Nimigean CM, Riegelhaupt PM.  2023.  Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.. Nat Commun. 14(1):1077.
Lansky S, Betancourt JMichael, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S.  2023.  A pentameric TRPV3 channel with a dilated pore.. Nature. 621(7977):206-214.
2024
Thon O, Wang Z, Schmidpeter PAM, Nimigean CM.  2024.  PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK.. Nat Commun. 15(1):8230.
Kim ED, Wu X, Lee S, Tibbs GR, Cunningham KP, Di Zanni E, Perez ME, Goldstein PA, Accardi A, H Larsson P et al..  2024.  Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants.. Nature.
2025
Agarwal S, Kim ED, Lee S, Simon A, Accardi A, Nimigean CM.  2025.  Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel.. Nat Commun. 16(1):1769.