Department of Anesthesiology
Journal Article
Liantonio A, Pusch M, Picollo A, Guida P, De Luca A, Pierno S, Fracchiolla G, Loiodice F, Tortorella P, Camerino DConte.  2004.  Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.. J Am Soc Nephrol. 15(1):13-20.
Jayaram H, Accardi A, Wu F, Williams C, Miller C.  2008.  Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.. Proc Natl Acad Sci U S A. 105(32):11194-9.
Accardi A, Kolmakova-Partensky L, Williams C, Miller C.  2004.  Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.. J Gen Physiol. 123(2):109-19.
Marchesi A, Gao X, Adaixo R, Rheinberger J, Stahlberg H, Nimigean C, Scheuring S.  2018.  An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel.. Nat Commun. 9(1):3978.
Osman V, Speigel I, Patel K, Hemmings HC.  2023.  Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons.. eNeuro. 10(8)
Ouyang W, Wang G, Hemmings HC.  2003.  Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.. Mol Pharmacol. 64(2):373-81.
Torturo CL, Zhou Z-Y, Ryan TA, Hemmings HC.  2019.  Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons.. eNeuro. 6(1)
Ouyang W, Jih T-Y, Zhang T-T, Correa AM, Hemmings HC.  2007.  Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.. J Pharmacol Exp Ther. 322(3):1076-83.
Baumgart JP, Zhou Z-Y, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC.  2015.  Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.. Proc Natl Acad Sci U S A. 112(38):11959-64.
Herold KF, Nau C, Ouyang W, Hemmings HC.  2009.  Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.. Anesthesiology. 111(3):591-9.
Jia F, Yue M, Chandra D, Homanics GE, Goldstein PA, Harrison NL.  2008.  Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus.. J Pharmacol Exp Ther. 324(3):1127-35.
Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC.  2017.  Isoflurane modulates activation and inactivation gating of the prokaryotic Na(+) channel NaChBac.. J Gen Physiol. 149(6):623-638.
Ying S-W, Werner DF, Homanics GE, Harrison NL, Goldstein PA.  2009.  Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.. Neuropharmacology. 56(2):438-47.
Zhao W, Zhang M, Liu J, Liang P, Wang R, Hemmings HC, Zhou C.  2019.  Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.. Anesthesiology. 131(1):94-104.
Platholi J, Herold KF, Hemmings HC, Halpain S.  2014.  Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.. PLoS One. 9(7):e102978.
Zhao W, Zhao S, Zhu T, Ou M, Zhang D, Sun H, Liu J, Chen X, Hemmings HC, Zhou C.  2021.  Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.. Anesthesiology.
Ming Q, Liou J-Y, Yang F, Li J, Chu C, Zhou Q, Wu D, Xu S, Luo P, Liang J et al..  2020.  Isoflurane-Induced Burst Suppression Is a Thalamus-Modulated, Focal-Onset Rhythm With Persistent Local Asynchrony and Variable Propagation Patterns in Rats.. Front Syst Neurosci. 14:599781.
Ouyang W, Hemmings HC.  2007.  Isoform-selective effects of isoflurane on voltage-gated Na+ channels.. Anesthesiology. 107(1):91-8.
Pryor KO, Veselis RA.  2016.  Isolated Forearm Test: Replicated, Relevant, and Unexplained.. Anesthesiology.
Pryor KO, Veselis RA.  2017.  Isolated Forearm Test: Replicated, Relevant, and Unexplained.. Anesthesiology. 126(2):202-204.
Roepke TK, Kanda VA, Purtell K, King EC, Lerner DJ, Abbott GW.  2011.  KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.. FASEB J. 25(12):4264-73.
Purtell K, Paroder-Belenitsky M, Reyna-Neyra A, Nicola JP, Koba W, Fine E, Carrasco N, Abbott GW.  2012.  The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake.. FASEB J. 26(8):3252-9.
McCoy JG, Rusinova R, Kim DM, Kowal J, Banerjee S, Cartagena AJaramillo, Thompson AN, Kolmakova-Partensky L, Stahlberg H, Andersen OS et al..  2014.  A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics.. J Biol Chem. 289(14):9535-46.
D'Ambra MN, Dedrick D, Savarese JJ.  1979.  Kearns-Sayer syndrome and pancuronium--succinylcholine-induced neuromuscular blockade.. Anesthesiology. 51(4):343-5.
Nicholson-Tomishima K, Ryan TA.  2004.  Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I.. Proc Natl Acad Sci U S A. 101(47):16648-52.