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Department of Anesthesiology

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Publications

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Ying S-W, Kanda VA, Hu Z, Purtell K, King EC, Abbott GW, Goldstein PA.  2012.  Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.. PLoS One. 7(8):e42756.
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Calder EL, Tchieu J, Steinbeck JA, Tu E, Keros S, Ying S-W, Jaiswal MK, Cornacchia D, Goldstein PA, Tabar V et al..  2015.  Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation.. J Neurosci. 35(33):11462-81.
Heuermann RJ, Jaramillo TC, Ying S-W, Suter BA, Lyman KA, Han Y, Lewis AS, Hampton TG, Shepherd GMG, Goldstein PA et al..  2016.  Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy.. Neurobiol Dis. 85:81-92.
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Ying S-W, Goldstein PA.  2005.  Propofol-block of SK channels in reticular thalamic neurons enhances GABAergic inhibition in relay neurons.. J Neurophysiol. 93(4):1935-48.
Ying S-W, Goldstein PA.  2005.  Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA(A) receptor chloride channels.. Mol Pain. 1:2.
Ying S-W, Abbas SY, Harrison NL, Goldstein PA.  2006.  Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons.. Eur J Neurosci. 23(2):465-80.
Goldstein PA, Elsen FP, Ying S-W, Ferguson C, Homanics GE, Harrison NL.  2002.  Prolongation of hippocampal miniature inhibitory postsynaptic currents in mice lacking the GABA(A) receptor alpha1 subunit.. J Neurophysiol. 88(6):3208-17.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
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Ying S-W, Werner DF, Homanics GE, Harrison NL, Goldstein PA.  2009.  Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.. Neuropharmacology. 56(2):438-47.
Lafaille FG, Pessach IM, Zhang S-Y, Ciancanelli MJ, Herman M, Abhyankar A, Ying S-W, Keros S, Goldstein PA, Mostoslavsky G et al..  2012.  Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.. Nature. 491(7426):769-73.
Mattusch C, Kratzer S, Buerge M, Kreuzer M, Engel T, Kopp C, Biel M, Hammelmann V, Ying S-W, Goldstein PA et al..  2015.  Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments.. Anesthesiology. 122(5):1047-59.
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Maroof AM, Keros S, Tyson JA, Ying S-W, Ganat YM, Merkle FT, Liu B, Goulburn A, Stanley EG, Elefanty AG et al..  2013.  Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells.. Cell Stem Cell. 12(5):559-72.
Ying S-W, Jia F, Abbas SY, Hofmann F, Ludwig A, Goldstein PA.  2007.  Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons.. J Neurosci. 27(32):8719-32.