Department of Anesthesiology
Author Title [ Type(Asc)] Year
Filters: Author is Accardi, Alessio  [Clear All Filters]
Journal Article
Falzone ME, Malvezzi M, Lee B-C, Accardi A.  2018.  Known structures and unknown mechanisms of TMEM16 scramblases and channels.. J Gen Physiol.
Accardi A, Kolmakova-Partensky L, Williams C, Miller C.  2004.  Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.. J Gen Physiol. 123(2):109-19.
Jayaram H, Accardi A, Wu F, Williams C, Miller C.  2008.  Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.. Proc Natl Acad Sci U S A. 105(32):11194-9.
Feng Z, Di Zanni E, Alvarenga O, Chakraborty S, Rychlik N, Accardi A.  2024.  In or out of the groove? Mechanisms of lipid scrambling by TMEM16 proteins. Cell Calcium. 121:102896.
Lee B-C, Khelashvili G, Falzone M, Menon AK, Weinstein H, Accardi A.  2018.  Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase.. Nat Commun. 9(1):3251.
Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, de Bernabé DBeltrán-V, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ et al..  2011.  A dystroglycan mutation associated with limb-girdle muscular dystrophy.. N Engl J Med. 364(10):939-46.
Khelashvili G, Falzone ME, Cheng X, Lee B-C, Accardi A, Weinstein H.  2019.  Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca-bound nhTMEM16.. Nat Commun. 10(1):4972.
Estévez R, Schroeder BC, Accardi A, Jentsch TJ, Pusch M.  2003.  Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.. Neuron. 38(1):47-59.
Basilio D, Noack K, Picollo A, Accardi A.  2014.  Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.. Nat Struct Mol Biol. 21(5):456-63.
Accardi A, Pusch M.  2003.  Conformational changes in the pore of CLC-0.. J Gen Physiol. 122(3):277-93.
Sokolova O, Accardi A, Gutierrez D, Lau A, Rigney M, Grigorieff N.  2003.  Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.. Proc Natl Acad Sci U S A. 100(22):12607-12.
Accardi A, Picollo A.  2010.  CLC channels and transporters: proteins with borderline personalities.. Biochim Biophys Acta. 1798(8):1457-64.
Accardi A.  2015.  CELL SIGNALING. Lipids link ion channels and cancer.. Science. 349(6250):789-90.
Malvezzi M, Chalat M, Janjusevic R, Picollo A, Terashima H, Menon AK, Accardi A.  2013.  Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.. Nat Commun. 4:2367.
Iyer R, Iverson TM, Accardi A, Miller C.  2002.  A biological role for prokaryotic ClC chloride channels.. Nature. 419(6908):715-8.
Picollo A, Malvezzi M, Houtman JCD, Accardi A.  2009.  Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.. Nat Struct Mol Biol. 16(12):1294-301.
Agarwal S, Kim ED, Lee S, Simon A, Accardi A, Nimigean CM.  2025.  Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel.. Nat Commun. 16(1):1769.
Leisle L, Lam K, Dehghani-Ghahnaviyeh S, Fortea E, Galpin JD, Ahern CA, Tajkhorshid E, Accardi A.  2022.  Backbone amides are determinants of Cl- selectivity in CLC ion channels.. Nat Commun. 13(1):7508.
Fortea E, Lee S, Chadda R, Argyros Y, Sandal P, Mahoney-Kruszka R, Ciftci HDidar, Falzone ME, Huysmans G, Robertson JL et al..  2024.  Author Correction: Structural basis of pH-dependent activation in a CLC transporter.. Nat Struct Mol Biol.