Department of Anesthesiology
Author Title Type [ Year(Asc)]
Filters: Author is Herold, Karl F  [Clear All Filters]
2024
Hollingworth D, Herold KF, Kelly G, Mykhaylyk VB, Xiang J, Zhang D, Wallace BA, Hemmings HC.  2024.  Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography.. bioRxiv.
2023
Eastman RT, Rusinova R, Herold KF, Huang X-P, Dranchak P, Voss TC, Rana S, Shrimp JH, White AD, Hemmings HC et al..  2023.  Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity.. bioRxiv.
2019
Zhou C, Johnson KW, Herold KF, Hemmings HC.  2019.  Differential Inhibition of Neuronal Sodium Channel Subtypes by the General Anesthetic Isoflurane.. J Pharmacol Exp Ther.
2017
Herold KF, R Sanford L, Lee W, Andersen OS, Hemmings HC.  2017.  Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties.. Proc Natl Acad Sci U S A.
Herold KF, Andersen OS, Hemmings HC.  2017.  Divergent effects of anesthetics on lipid bilayer properties and sodium channel function.. Eur Biophys J. 46(7):617-626.
Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC.  2017.  Isoflurane modulates activation and inactivation gating of the prokaryotic Na(+) channel NaChBac.. J Gen Physiol. 149(6):623-638.
Johnson KW, Herold KF, Milner TA, Hemmings HC, Platholi J.  2017.  Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus.. J Comp Neurol. 525(16):3563-3578.
2014
Platholi J, Herold KF, Hemmings HC, Halpain S.  2014.  Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.. PLoS One. 9(7):e102978.
Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al..  2014.  Phytochemicals perturb membranes and promiscuously alter protein function.. ACS Chem Biol. 9(8):1788-98.
Herold KF, R Sanford L, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC.  2014.  Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.. J Gen Physiol. 144(6):545-60.
2013
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.
2012
Herold KF, Hemmings HC.  2012.  Sodium channels as targets for volatile anesthetics.. Front Pharmacol. 3:50.
2011
Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS.  2011.  Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.. J Gen Physiol. 138(2):249-70.
2009
Ouyang W, Herold KF, Hemmings HC.  2009.  Comparative effects of halogenated inhaled anesthetics on voltage-gated Na+ channel function.. Anesthesiology. 110(3):582-90.
Herold KF, Nau C, Ouyang W, Hemmings HC.  2009.  Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.. Anesthesiology. 111(3):591-9.