Publications

Menny A, Lefebvre SN, Schmidpeter PAm, Drège E, Fourati Z, Delarue M, Edelstein SJ, Nimigean CM, Joseph D, Corringer P-J.  2017.  Identification of a pre-active conformation of a pentameric channel receptor.. Elife. 6

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Purtell K, Gingrich KJ, OuYang W, Herold KF, Hemmings HC.  2015.  Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.. Br J Anaesth. 115(1):112-21.

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Accardi A.  2015.  CELL SIGNALING. Lipids link ion channels and cancer.. Science. 349(6250):789-90.

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Basilio D, Accardi A.  2015.  A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters.. J Vis Exp. (98)

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Roepke TK, Kanda VA, Purtell K, King EC, Lerner DJ, Abbott GW.  2011.  KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.. FASEB J. 25(12):4264-73.

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Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.

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Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS.  2011.  Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.. J Gen Physiol. 138(2):249-70.

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Picollo A, Malvezzi M, Accardi A.  2010.  Proton block of the CLC-5 Cl-/H+ exchanger.. J Gen Physiol. 135(6):653-9.

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Gradogna A, Babini E, Picollo A, Pusch M.  2010.  A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.. J Gen Physiol. 136(3):311-23.

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Jia F, Yue M, Chandra D, Keramidas A, Goldstein PA, Homanics GE, Harrison NL.  2008.  Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus.. J Neurosci. 28(1):106-15.

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Ouyang W, Hemmings HC.  2007.  Isoform-selective effects of isoflurane on voltage-gated Na+ channels.. Anesthesiology. 107(1):91-8.

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Abbas SY, Ying S-W, Goldstein PA.  2006.  Compartmental distribution of hyperpolarization-activated cyclic-nucleotide-gated channel 2 and hyperpolarization-activated cyclic-nucleotide-gated channel 4 in thalamic reticular and thalamocortical relay neurons.. Neuroscience. 141(4):1811-25.

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Ying S-W, Abbas SY, Harrison NL, Goldstein PA.  2006.  Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons.. Eur J Neurosci. 23(2):465-80.

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Ouyang W, Hemmings HC.  2005.  Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals.. J Pharmacol Exp Ther. 312(2):801-8.

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Jia F, Pignataro L, Schofield CM, Yue M, Harrison NL, Goldstein PA.  2005.  An extrasynaptic GABAA receptor mediates tonic inhibition in thalamic VB neurons.. J Neurophysiol. 94(6):4491-501.

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Cacheaux LP, Topf N, Tibbs GR, Schaefer UR, Levi R, Harrison NL, Abbott GW, Goldstein PA.  2005.  Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.. J Pharmacol Exp Ther. 315(2):517-25.

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Cropper EC, Evans CG, Jing J, Klein A, Proekt A, Romero A, Rosen SC.  2004.  Regulation of afferent transmission in the feeding circuitry of Aplysia.. Acta Biol Hung. 55(1-4):211-20.

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Nimigean CM, Chappie JS, Miller C.  2003.  Electrostatic tuning of ion conductance in potassium channels.. Biochemistry. 42(31):9263-8.

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Moran O, Picollo A, Conti F.  2003.  Tonic and phasic guanidinium toxin-block of skeletal muscle Na channels expressed in Mammalian cells.. Biophys J. 84(5):2999-3006.

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Nimigean CM, Miller C.  2002.  Na+ block and permeation in a K+ channel of known structure.. J Gen Physiol. 120(3):323-35.

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Qian X, Nimigean CM, Niu X, Moss BL, Magleby KL.  2002.  Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels.. J Gen Physiol. 120(6):829-43.

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Ratnakumari L, Vysotskaya TN, Duch DS, Hemmings HC.  2000.  Differential effects of anesthetic and nonanesthetic cyclobutanes on neuronal voltage-gated sodium channels.. Anesthesiology. 92(2):529-41.

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Nimigean CM, Magleby KL.  2000.  Functional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism.. J Gen Physiol. 115(6):719-36.

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Lingameneni R, Vysotskaya TN, Duch DS, Hemmings HC.  2000.  Inhibition of voltage-dependent sodium channels by Ro 31-8220, a 'specific' protein kinase C inhibitor.. FEBS Lett. 473(2):265-8.

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Baba H, Goldstein PA, Okamoto M, Kohno T, Ataka T, Yoshimura M, Shimoji K.  2000.  Norepinephrine facilitates inhibitory transmission in substantia gelatinosa of adult rat spinal cord (part 2): effects on somatodendritic sites of GABAergic neurons.. Anesthesiology. 92(2):485-92.

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