Department of Anesthesiology
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2016
Hara M, Zhou Z-Y, Hemmings HC.  2016.  α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons.. Anesthesiology.
2015
Giambrone GP, Wu X, Gaber-Baylis LK, Bhat AU, Zabih R, Altorki NK, Fleischut PM, Stiles BM.  2015.  Incidence and implications of postoperative supraventricular tachycardia after pulmonary lobectomy.. J Thorac Cardiovasc Surg.
Baumgart JP, Zhou Z-Y, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC.  2015.  Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.. Proc Natl Acad Sci U S A. 112(38):11959-64.
Jaiswal MK, Keros S, Zhao M, Inan M, Schwartz TH, Anderson SA, Homanics GE, Goldstein PA.  2015.  Reduction in focal ictal activity following transplantation of MGE interneurons requires expression of the GABAA receptor α4 subunit.. Front Cell Neurosci. 9:127.
2014
Diaz LL, Zhang J, Heerdt PM.  2014.  Comparative pharmacodynamics of pancuronium, cisatracurium, and CW002 in rabbits.. J Am Assoc Lab Anim Sci. 53(3):283-9.
Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al..  2014.  Phytochemicals perturb membranes and promiscuously alter protein function.. ACS Chem Biol. 9(8):1788-98.
2012
Lafaille FG, Pessach IM, Zhang S-Y, Ciancanelli MJ, Herman M, Abhyankar A, Ying S-W, Keros S, Goldstein PA, Mostoslavsky G et al..  2012.  Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.. Nature. 491(7426):769-73.
Zhu J, Choi W-S, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D et al..  2012.  Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.. Sci Transl Med. 4(125):125ra32.
Zhu J, Choi W-S, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D et al..  2012.  Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.. Sci Transl Med. 4(125):125ra32.
2011
Englund EE, Neumann S, Eliseeva E, McCoy JG, Titus S, Zheng W, Southall N, Shin P, Leister W, Thomas CJ et al..  2011.  The Synthesis and Evaluation of Dihydroquinazolin-4-ones and Quinazolin-4-ones as Thyroid Stimulating Hormone Receptor Agonists.. Medchemcomm. 2(10):1016-1020.
2010
Zhang Y, Guzinski M, Eger EI, Laster MJ, Sharma M, Harris RA, Hemmings HC.  2010.  Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats.. Br J Pharmacol. 159(4):872-8.
Sunaga H, Zhang Y, Savarese JJ, Emala CW.  2010.  Gantacurium and CW002 do not potentiate muscarinic receptor-mediated airway smooth muscle constriction in guinea pigs.. Anesthesiology. 112(4):892-9.
Zifarelli G, Liantonio A, Gradogna A, Picollo A, Gramegna G, De Bellis M, Murgia AR, Babini E, D Camerino C, Pusch M.  2010.  Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.. Br J Pharmacol. 160(7):1652-61.
McCoy JG, Marugan JJ, Liu K, Zheng W, Southall N, Huang W, Heilig M, Austin CP.  2010.  Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines as antagonists of the Neuropeptide S Receptor.. ACS Chem Neurosci. 1(8):559-574.
2009
Tedore TR, Yadeau JT, Maalouf DB, Weiland AJ, Tong-Ngork S, Wukovits B, Paroli L, Urban MK, Zayas VM, Wu A et al..  2009.  Comparison of the transarterial axillary block and the ultrasound-guided infraclavicular block for upper extremity surgery: a prospective randomized trial.. Reg Anesth Pain Med. 34(4):361-5.
Chatterjee O, Taylor LA, Ahmed S, Nagaraj S, Hall JJ, Finckbeiner SM, Chan PS, Suda N, King JT, Zeeman ML et al..  2009.  Social stress alters expression of large conductance calcium-activated potassium channel subunits in mouse adrenal medulla and pituitary glands.. J Neuroendocrinol. 21(3):167-76.
2008
Zhang Y, Sharma M, Eger EI, Laster MJ, Hemmings HC, R Harris A.  2008.  Intrathecal veratridine administration increases minimum alveolar concentration in rats.. Anesth Analg. 107(3):875-8.
Liantonio A, Picollo A, Carbonara G, Fracchiolla G, Tortorella P, Loiodice F, Laghezza A, Babini E, Zifarelli G, Pusch M et al..  2008.  Molecular switch for CLC-K Cl- channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.. Proc Natl Acad Sci U S A. 105(4):1369-73.
Amar D, Desiderio DP, Heerdt PM, Kolker AC, Zhang H, Thaler HT.  2008.  Practice patterns in choice of left double-lumen tube size for thoracic surgery.. Anesth Analg. 106(2):379-83,tableofcontents.
Proekt A, Wong J, Zhurov Y, Kozlova N, Weiss KR, Brezina V.  2008.  Predicting adaptive behavior in the environment from central nervous system dynamics.. PLoS One. 3(11):e3678.
Zhang TT, Platholi J, Heerdt PM, Hemmings HC, Tung HYL.  2008.  Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation.. Metab Brain Dis. 23(1):95-104.
Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN, Thorson JS.  2008.  Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.. J Biol Chem. 283(33):22628-36.
2007
Amar D, Zhang H, Park B, Heerdt PM, Fleisher M, Thaler HT.  2007.  Inflammation and outcome after general thoracic surgery.. Eur J Cardiothorac Surg. 32(3):431-4.
Ouyang W, Jih T-Y, Zhang T-T, Correa AM, Hemmings HC.  2007.  Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.. J Pharmacol Exp Ther. 322(3):1076-83.
Chiu P-L, Pagel MD, Evans J, Chou H-T, Zeng X, Gipson B, Stahlberg H, Nimigean CM.  2007.  The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MloK1 at 16 A resolution.. Structure. 15(9):1053-64.