Transcatheter Mitral Valve Interventions for Mitral Regurgitation: A Review of Mitral Annuloplasty, Valve Replacement, and Chordal Repair Devices.

TitleTranscatheter Mitral Valve Interventions for Mitral Regurgitation: A Review of Mitral Annuloplasty, Valve Replacement, and Chordal Repair Devices.
Publication TypeJournal Article
Year of Publication2022
AuthorsKhatib D, Neuburger PJ, Pan S, Rong LQ
JournalJ Cardiothorac Vasc Anesth
Volume36
Issue10
Pagination3887-3903
Date Published2022 Oct
ISSN1532-8422
KeywordsCardiac Catheterization, Heart Valve Prosthesis Implantation, Humans, Mitral Valve, Mitral Valve Annuloplasty, Mitral Valve Insufficiency, Treatment Outcome
Abstract

Significant mitral regurgitation (MR) is the most common valvular disease in the United States in patients older than 75. However, many patients with severe MR are at a high risk for surgical repair due to other significant comorbidities. Over the past decade, many transcatheter mitral valve devices have been studied that address the different mechanisms of MR, but only a few have received a Conformité Européene (CE) mark or United States Food and Drug Administration (FDA) approval. The Carillon, Cardioband, and Mitralign all received CE marking for percutaneous mitral annuloplasty, while the Tendyne and SAPIEN 3 received a CE mark and FDA approval, respectively, for transcatheter mitral valve replacement. Finally, the NeoChord DS 1000 received a CE mark for transcatheter chordal repair. Each of these devices is reviewed in detail, including device indications, performance in clinical trials, anesthetic management, intraprocedural imaging guidance, and postprocedural complications. Although percutaneous devices will appear and disappear from use, understanding the procedural considerations remains highly relevant, as these key principles will apply to the next generation of transcatheter valve interventions.

DOI10.1053/j.jvca.2022.05.005
Alternate JournalJ Cardiothorac Vasc Anesth
PubMed ID35871885