Department of Anesthesiology

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The rational pharmacology of digoxin.

TitleThe rational pharmacology of digoxin.
Publication TypeJournal Article
Year of Publication1992
AuthorsHeerdt PM, Heerdt ME
JournalJ Clin Anesth
Volume4
Issue5
Pagination419-35
Date Published1992 Sep-Oct
ISSN0952-8180
KeywordsDigoxin, Humans
Abstract

Although digoxin remains one of the most widely prescribed drugs in the United States, potential pharmacodynamic and pharmacokinetic interactions between this compound and other drugs, diseases, and events commonly encountered in the perioperative period remain largely unappreciated. Furthermore, the therapeutic benefit of discontinuing or initiating digoxin treatment preoperatively remains unclear. We present a basic review of current knowledge regarding digoxin pharmacology and examine those concepts from the perspective of clinical anesthesiologists.

Alternate JournalJ Clin Anesth
PubMed ID1389200