Department of Anesthesiology

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Malignant hyperthermia following systemic rewarming after hypothermic cardiopulmonary bypass.

TitleMalignant hyperthermia following systemic rewarming after hypothermic cardiopulmonary bypass.
Publication TypeJournal Article
Year of Publication2006
AuthorsLichtman AD, Oribabor C
JournalAnesth Analg
Volume102
Issue2
Pagination372-5
Date Published2006 Feb
ISSN1526-7598
KeywordsCardiopulmonary Bypass, Coronary Artery Bypass, Humans, Hypothermia, Induced, Male, Malignant Hyperthermia, Middle Aged, Postoperative Complications, Rewarming
Abstract

Malignant hyperthermia (MH) is a rare hypermetabolic disorder of skeletal muscle that can be fatal if not recognized and treated aggressively. We describe a patient with a suspected family history of MH who developed hyperpyrexia, acidosis, and hypermetabolism after cardiac surgery despite a nontriggering anesthetic. No drugs were identified as being causative and we theorize that systemic rewarming was the inciting cause of MH in this MH-susceptible individual via a mechanism similar to heat stroke.

DOI10.1213/01.ane.0000189596.70694.36
Alternate JournalAnesth. Analg.
PubMed ID16428525