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Department of Anesthesiology

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Malignant hyperthermia following systemic rewarming after hypothermic cardiopulmonary bypass.

TitleMalignant hyperthermia following systemic rewarming after hypothermic cardiopulmonary bypass.
Publication TypeJournal Article
Year of Publication2006
AuthorsLichtman AD, Oribabor C
JournalAnesth Analg
Date Published2006 Feb
KeywordsCardiopulmonary Bypass, Coronary Artery Bypass, Humans, Hypothermia, Induced, Male, Malignant Hyperthermia, Middle Aged, Postoperative Complications, Rewarming

Malignant hyperthermia (MH) is a rare hypermetabolic disorder of skeletal muscle that can be fatal if not recognized and treated aggressively. We describe a patient with a suspected family history of MH who developed hyperpyrexia, acidosis, and hypermetabolism after cardiac surgery despite a nontriggering anesthetic. No drugs were identified as being causative and we theorize that systemic rewarming was the inciting cause of MH in this MH-susceptible individual via a mechanism similar to heat stroke.

Alternate JournalAnesth. Analg.
PubMed ID16428525