| Title | General anesthesia for cesarean delivery in a patient with paroxysmal nocturnal hemoglobinuria and thrombocytopenia. |
| Publication Type | Journal Article |
| Year of Publication | 2004 |
| Authors | Kjaer K, Comerford M, Gadalla F |
| Journal | Anesth Analg |
| Volume | 98 |
| Issue | 5 |
| Pagination | 1471-2, table of contents |
| Date Published | 2004 May |
| ISSN | 0003-2999 |
| Keywords | Adult, Anesthesia, General, Anesthesia, Obstetrical, Cesarean Section, Female, Hemoglobinuria, Paroxysmal, Humans, Male, Pregnancy, Pregnancy Outcome, Thrombocytopenia |
| Abstract | UNLABELLED: Pregnancy in patients with paroxysmal nocturnal hemoglobinuria (PNH) increases the risk of complement activation, hemolysis, and thrombosis. We describe the anesthetic management of a patient with PNH who underwent general anesthesia for cesarean delivery. Steroids, heparin, and blood products were administered early to minimize the likelihood of a hematologic emergency. IMPLICATIONS: Pregnancy in patients with paroxysmal nocturnal hemoglobinuria increases the risk of hemolysis, thrombosis, anemia, and thrombocytopenia. We describe the anesthetic management of a patient with paroxysmal nocturnal hemoglobinuria and thrombocytopenia who underwent general anesthesia for cesarean delivery. |
| Alternate Journal | Anesth. Analg. |
| PubMed ID | 15105233 |