Department of Anesthesiology
Author Title Type [ Year(Desc)]
Filters: Keyword is Sodium Channels  [Clear All Filters]
1995
Schlame M, Hemmings HC.  1995.  Inhibition by volatile anesthetics of endogenous glutamate release from synaptosomes by a presynaptic mechanism.. Anesthesiology. 82(6):1406-16.
1996
Ratnakumari L, Hemmings HC.  1996.  Inhibition by propofol of [3H]-batrachotoxinin-A 20-alpha-benzoate binding to voltage-dependent sodium channels in rat cortical synaptosomes.. Br J Pharmacol. 119(7):1498-504.
1997
Ratnakumari L, Hemmings HC.  1997.  Effects of propofol on sodium channel-dependent sodium influx and glutamate release in rat cerebrocortical synaptosomes.. Anesthesiology. 86(2):428-39.
1998
Ratnakumari L, Hemmings HC.  1998.  Inhibition of presynaptic sodium channels by halothane.. Anesthesiology. 88(4):1043-54.
1999
Lingamaneni R, Hemmings HC.  1999.  Effects of anticonvulsants on veratridine- and KCl-evoked glutamate release from rat cortical synaptosomes.. Neurosci Lett. 276(2):127-30.
2000
Ratnakumari L, Vysotskaya TN, Duch DS, Hemmings HC.  2000.  Differential effects of anesthetic and nonanesthetic cyclobutanes on neuronal voltage-gated sodium channels.. Anesthesiology. 92(2):529-41.
2001
Lingamaneni R, Birch ML, Hemmings HC.  2001.  Widespread inhibition of sodium channel-dependent glutamate release from isolated nerve terminals by isoflurane and propofol.. Anesthesiology. 95(6):1460-6.
2003
Lingamaneni R, Hemmings HC.  2003.  Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na+ channels, Ca2+ channels, and GABA(A) receptors.. Br J Anaesth. 90(2):199-211.
Ouyang W, Wang G, Hemmings HC.  2003.  Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.. Mol Pharmacol. 64(2):373-81.
Moran O, Picollo A, Conti F.  2003.  Tonic and phasic guanidinium toxin-block of skeletal muscle Na channels expressed in Mammalian cells.. Biophys J. 84(5):2999-3006.
2004
Hemmings HC.  2004.  Neuroprotection by Na+ channel blockade.. J Neurosurg Anesthesiol. 16(1):100-1.
2007
Ouyang W, Jih T-Y, Zhang T-T, Correa AM, Hemmings HC.  2007.  Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.. J Pharmacol Exp Ther. 322(3):1076-83.
Ouyang W, Hemmings HC.  2007.  Isoform-selective effects of isoflurane on voltage-gated Na+ channels.. Anesthesiology. 107(1):91-8.
2008
Zhang Y, Sharma M, Eger EI, Laster MJ, Hemmings HC, R Harris A.  2008.  Intrathecal veratridine administration increases minimum alveolar concentration in rats.. Anesth Analg. 107(3):875-8.
Eger EI, Raines DE, Shafer SL, Hemmings HC, Sonner JM.  2008.  Is a new paradigm needed to explain how inhaled anesthetics produce immobility? Anesth Analg. 107(3):832-48.
2009
Ouyang W, Herold KF, Hemmings HC.  2009.  Comparative effects of halogenated inhaled anesthetics on voltage-gated Na+ channel function.. Anesthesiology. 110(3):582-90.
Herold KF, Nau C, Ouyang W, Hemmings HC.  2009.  Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.. Anesthesiology. 111(3):591-9.
Hemmings HC.  2009.  Sodium channels and the synaptic mechanisms of inhaled anaesthetics.. Br J Anaesth. 103(1):61-9.
2010
Zhang Y, Guzinski M, Eger EI, Laster MJ, Sharma M, Harris RA, Hemmings HC.  2010.  Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats.. Br J Pharmacol. 159(4):872-8.
Westphalen RI, Yu J, Krivitski M, Jih T-Y, Hemmings HC.  2010.  Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.. J Neurochem. 113(6):1611-20.
2011
Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS.  2011.  Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.. J Gen Physiol. 138(2):249-70.
2015
Purtell K, Gingrich KJ, OuYang W, Herold KF, Hemmings HC.  2015.  Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.. Br J Anaesth. 115(1):112-21.
2017
Herold KF, Andersen OS, Hemmings HC.  2017.  Divergent effects of anesthetics on lipid bilayer properties and sodium channel function.. Eur Biophys J. 46(7):617-626.