Department of Anesthesiology
Author Title Type [ Year(Asc)]
Filters: Keyword is Dose-Response Relationship, Drug  [Clear All Filters]
2014
Herold KF, R Sanford L, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC.  2014.  Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.. J Gen Physiol. 144(6):545-60.
2013
Westphalen RI, Desai KM, Hemmings HC.  2013.  Presynaptic inhibition of the release of multiple major central nervous system neurotransmitter types by the inhaled anaesthetic isoflurane.. Br J Anaesth. 110(4):592-9.
2012
Storer KP, Reeke GN.  2012.  γ-Aminobutyric acid receptor type A receptor potentiation reduces firing of neuronal assemblies in a computational cortical model.. Anesthesiology. 117(4):780-90.
2011
Lien CA.  2011.  Development and potential clinical impairment of ultra-short-acting neuromuscular blocking agents.. Br J Anaesth. 107 Suppl 1:i60-71.
Kopman AF, Lien CA, Naguib M.  2011.  Neuromuscular dose-response studies: determining sample size.. Br J Anaesth. 106(2):194-8.
2010
Zhang Y, Guzinski M, Eger EI, Laster MJ, Sharma M, Harris RA, Hemmings HC.  2010.  Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats.. Br J Pharmacol. 159(4):872-8.
Sunaga H, Malhotra JK, Yoon E, Savarese JJ, Heerdt PM.  2010.  Cysteine reversal of the novel neuromuscular blocking drug CW002 in dogs: pharmacodynamics, acute cardiovascular effects, and preliminary toxicology.. Anesthesiology. 112(4):900-9.
Kopman AF, Lien CA, Naguib M.  2010.  Determining the potency of neuromuscular blockers: are traditional methods flawed? Br J Anaesth. 104(6):705-10.
Sunaga H, Zhang Y, Savarese JJ, Emala CW.  2010.  Gantacurium and CW002 do not potentiate muscarinic receptor-mediated airway smooth muscle constriction in guinea pigs.. Anesthesiology. 112(4):892-9.
Zifarelli G, Liantonio A, Gradogna A, Picollo A, Gramegna G, De Bellis M, Murgia AR, Babini E, D Camerino C, Pusch M.  2010.  Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.. Br J Pharmacol. 160(7):1652-61.
Lien CA.  2010.  Neostigmine: how much is necessary for patients who receive a nondepolarizing neuromuscular blocking agent? Anesthesiology. 112(1):16-8.
Heerdt PM, Malhotra JK, Pan BY, Sunaga H, Savarese JJ.  2010.  Pharmacodynamics and cardiopulmonary side effects of CW002, a cysteine-reversible neuromuscular blocking drug in dogs.. Anesthesiology. 112(4):910-6.
Savarese JJ, McGilvra JD, Sunaga H, Belmont MR, Van Ornum SG, Savard PM, Heerdt PM.  2010.  Rapid chemical antagonism of neuromuscular blockade by L-cysteine adduction to and inactivation of the olefinic (double-bonded) isoquinolinium diester compounds gantacurium (AV430A), CW 002, and CW 011.. Anesthesiology. 113(1):58-73.
Westphalen RI, Yu J, Krivitski M, Jih T-Y, Hemmings HC.  2010.  Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.. J Neurochem. 113(6):1611-20.
2009
Ouyang W, Herold KF, Hemmings HC.  2009.  Comparative effects of halogenated inhaled anesthetics on voltage-gated Na+ channel function.. Anesthesiology. 110(3):582-90.
Ying S-W, Werner DF, Homanics GE, Harrison NL, Goldstein PA.  2009.  Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.. Neuropharmacology. 56(2):438-47.
Westphalen RI, Gomez RS, Hemmings HC.  2009.  Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane.. Br J Anaesth. 102(3):355-60.
Veselis RA, Pryor KO, Reinsel RA, Li Y, Mehta M, Johnson R.  2009.  Propofol and midazolam inhibit conscious memory processes very soon after encoding: an event-related potential study of familiarity and recollection in volunteers.. Anesthesiology. 110(2):295-312.
2008
Zhang Y, Sharma M, Eger EI, Laster MJ, Hemmings HC, R Harris A.  2008.  Intrathecal veratridine administration increases minimum alveolar concentration in rats.. Anesth Analg. 107(3):875-8.
Jia F, Yue M, Chandra D, Homanics GE, Goldstein PA, Harrison NL.  2008.  Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus.. J Pharmacol Exp Ther. 324(3):1127-35.
Veselis RA, Pryor KO, Reinsel RA, Mehta M, Pan H, Johnson R.  2008.  Low-dose propofol-induced amnesia is not due to a failure of encoding: left inferior prefrontal cortex is still active.. Anesthesiology. 109(2):213-24.
Jia F, Yue M, Chandra D, Keramidas A, Goldstein PA, Homanics GE, Harrison NL.  2008.  Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus.. J Neurosci. 28(1):106-15.
2007
Nimigean CM, Pagel MD.  2007.  Ligand binding and activation in a prokaryotic cyclic nucleotide-modulated channel.. J Mol Biol. 371(5):1325-37.
2006
Deau JTYa, Heerdt PM, The AHS, Wang Q.  2006.  Hemodynamic effects of di-sec-butyl phenol, an anesthetic substituted phenol.. Pharmacology. 76(3):117-22.
Ying S-W, Abbas SY, Harrison NL, Goldstein PA.  2006.  Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons.. Eur J Neurosci. 23(2):465-80.