Department of Anesthesiology
Author Title Type [ Year(Asc)]
Filters: Keyword is Protein Conformation  [Clear All Filters]
2025
Agarwal S, Kim ED, Lee S, Simon A, Accardi A, Nimigean CM.  2025.  Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel.. Nat Commun. 16(1):1769.
Riel EB, Bu W, Joseph TT, Khajoueinejad L, Eckenhoff RG, Riegelhaupt PM.  2025.  The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel.. Proc Natl Acad Sci U S A. 122(14):e2421654122.
Jiang Y, Wang Z, Scheuring S.  2025.  A structural biology compatible file format for atomic force microscopy.. Nat Commun. 16(1):1671.
2023
Scheuring S.  2023.  Forces and energetics of the canonical tetrameric cation channel gating.. Proc Natl Acad Sci U S A. 120(28):e2221616120.
2015
Picollo A, Malvezzi M, Accardi A.  2015.  TMEM16 proteins: unknown structure and confusing functions.. J Mol Biol. 427(1):94-105.
2014
Corral-Rodríguez MÁngeles, Stuiver M, Abascal-Palacios G, Diercks T, Oyenarte I, Ereño-Orbea J, de Opakua AIbáñez, Blanco FJ, Encinar JAntonio, Spiwok V et al..  2014.  Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.. Biochem J. 464(1):23-34.
2013
Posson DJ, McCoy JG, Nimigean CM.  2013.  The voltage-dependent gate in MthK potassium channels is located at the selectivity filter.. Nat Struct Mol Biol. 20(2):159-66.
2011
Cheng WWL, McCoy JG, Thompson AN, Nichols CG, Nimigean CM.  2011.  Mechanism for selectivity-inactivation coupling in KcsA potassium channels.. Proc Natl Acad Sci U S A. 108(13):5272-7.
2010
Bae E, Bitto E, Bingman CA, McCoy JG, Wesenberg GE, Phillips GN.  2010.  Crystal structure of an eIF4G-like protein from Danio rerio.. Proteins. 78(7):1803-6.
Picollo A, Malvezzi M, Accardi A.  2010.  Proton block of the CLC-5 Cl-/H+ exchanger.. J Gen Physiol. 135(6):653-9.
2009
Picollo A, Malvezzi M, Houtman JCD, Accardi A.  2009.  Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.. Nat Struct Mol Biol. 16(12):1294-301.
2008
Bitto E, Bingman CA, Kondrashov DA, McCoy JG, Bannen RM, Wesenberg GE, Phillips GN.  2008.  Structure and dynamics of gamma-SNAP: insight into flexibility of proteins from the SNAP family.. Proteins. 70(1):93-104.
Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN, Thorson JS.  2008.  Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.. J Biol Chem. 283(33):22628-36.
2007
Bitto E, Bingman CA, Wesenberg GE, McCoy JG, Phillips GN.  2007.  Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.. Proc Natl Acad Sci U S A. 104(2):456-61.
Chiu P-L, Pagel MD, Evans J, Chou H-T, Zeng X, Gipson B, Stahlberg H, Nimigean CM.  2007.  The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MloK1 at 16 A resolution.. Structure. 15(9):1053-64.
2006
McCoy JG, Arabshahi A, Bitto E, Bingman CA, Ruzicka FJ, Frey PA, Phillips GN.  2006.  Structure and mechanism of an ADP-glucose phosphorylase from Arabidopsis thaliana.. Biochemistry. 45(10):3154-62.
McCoy JG, Bingman CA, Bitto E, Holdorf MM, Makaroff CA, Phillips GN.  2006.  Structure of an ETHE1-like protein from Arabidopsis thaliana.. Acta Crystallogr D Biol Crystallogr. 62(Pt 9):964-70.
Bitto E, Bingman CA, Wesenberg GE, McCoy JG, Phillips GN.  2006.  Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.. J Biol Chem. 281(29):20521-9.
2005
Accardi A, Walden M, Nguitragool W, Jayaram H, Williams C, Miller C.  2005.  Separate ion pathways in a Cl-/H+ exchanger.. J Gen Physiol. 126(6):563-70.
2004
Nimigean CM, Shane T, Miller C.  2004.  A cyclic nucleotide modulated prokaryotic K+ channel.. J Gen Physiol. 124(3):203-10.
Accardi A, Miller C.  2004.  Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels.. Nature. 427(6977):803-7.
2003
Sokolova O, Accardi A, Gutierrez D, Lau A, Rigney M, Grigorieff N.  2003.  Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.. Proc Natl Acad Sci U S A. 100(22):12607-12.
Nimigean CM, Chappie JS, Miller C.  2003.  Electrostatic tuning of ion conductance in potassium channels.. Biochemistry. 42(31):9263-8.
1995
Hemmings HC, Adamo AI, Hoffman MM.  1995.  Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C.. Anesth Analg. 81(6):1216-22.
1986
Williams KR, Hemmings HC, LoPresti MB, Konigsberg WH, Greengard P.  1986.  DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.. J Biol Chem. 261(4):1890-903.