Department of Anesthesiology
Author Title Type [ Year(Desc)]
Filters: Keyword is Models, Molecular  [Clear All Filters]
2000
Nimigean CM, Magleby KL.  2000.  Functional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism.. J Gen Physiol. 115(6):719-36.
Eldin S, Forget AL, Lindenmuth DM, Logan KM, Knight KL.  2000.  Mutations in the N-terminal region of RecA that disrupt the stability of free protein oligomers but not RecA-DNA complexes.. J Mol Biol. 299(1):91-101.
2003
Sokolova O, Accardi A, Gutierrez D, Lau A, Rigney M, Grigorieff N.  2003.  Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.. Proc Natl Acad Sci U S A. 100(22):12607-12.
2004
Accardi A, Miller C.  2004.  Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels.. Nature. 427(6977):803-7.
2006
Porotto M, Fornabaio M, Greengard O, Murrell MT, Kellogg GE, Moscona A.  2006.  Paramyxovirus receptor-binding molecules: engagement of one site on the hemagglutinin-neuraminidase protein modulates activity at the second site.. J Virol. 80(3):1204-13.
McCoy JG, Arabshahi A, Bitto E, Bingman CA, Ruzicka FJ, Frey PA, Phillips GN.  2006.  Structure and mechanism of an ADP-glucose phosphorylase from Arabidopsis thaliana.. Biochemistry. 45(10):3154-62.
McCoy JG, Bailey LJ, Bitto E, Bingman CA, Aceti DJ, Fox BG, Phillips GN.  2006.  Structure and mechanism of mouse cysteine dioxygenase.. Proc Natl Acad Sci U S A. 103(9):3084-9.
McCoy JG, Bingman CA, Bitto E, Holdorf MM, Makaroff CA, Phillips GN.  2006.  Structure of an ETHE1-like protein from Arabidopsis thaliana.. Acta Crystallogr D Biol Crystallogr. 62(Pt 9):964-70.
Bitto E, Bingman CA, Wesenberg GE, McCoy JG, Phillips GN.  2006.  Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.. J Biol Chem. 281(29):20521-9.
2007
R Johnson J, McCoy JG, Bingman CA, Phillips GN, Raines RT.  2007.  Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.. J Mol Biol. 368(2):434-49.
McCoy JG, Bitto E, Bingman CA, Wesenberg GE, Bannen RM, Kondrashov DA, Phillips GN.  2007.  Structure and dynamics of UDP-glucose pyrophosphorylase from Arabidopsis thaliana with bound UDP-glucose and UTP.. J Mol Biol. 366(3):830-41.
Bitto E, Bingman CA, Wesenberg GE, McCoy JG, Phillips GN.  2007.  Structure of aspartoacylase, the brain enzyme impaired in Canavan disease.. Proc Natl Acad Sci U S A. 104(2):456-61.
Chiu P-L, Pagel MD, Evans J, Chou H-T, Zeng X, Gipson B, Stahlberg H, Nimigean CM.  2007.  The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MloK1 at 16 A resolution.. Structure. 15(9):1053-64.
2008
Thompson AN, Posson DJ, Parsa PV, Nimigean CM.  2008.  Molecular mechanism of pH sensing in KcsA potassium channels.. Proc Natl Acad Sci U S A. 105(19):6900-5.
Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN, Thorson JS.  2008.  Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.. J Biol Chem. 283(33):22628-36.
Levin EJ, Elsen NL, Seder KD, McCoy JG, Fox BG, Phillips GN.  2008.  X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus.. Acta Crystallogr D Biol Crystallogr. 64(Pt 9):933-40.
2009
Picollo A, Malvezzi M, Houtman JCD, Accardi A.  2009.  Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.. Nat Struct Mol Biol. 16(12):1294-301.
2010
Bae E, Bitto E, Bingman CA, McCoy JG, Wesenberg GE, Phillips GN.  2010.  Crystal structure of an eIF4G-like protein from Danio rerio.. Proteins. 78(7):1803-6.
Zifarelli G, Liantonio A, Gradogna A, Picollo A, Gramegna G, De Bellis M, Murgia AR, Babini E, D Camerino C, Pusch M.  2010.  Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.. Br J Pharmacol. 160(7):1652-61.
Gradogna A, Babini E, Picollo A, Pusch M.  2010.  A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.. J Gen Physiol. 136(3):311-23.
Tanabe M, Nimigean CM, Iverson TM.  2010.  Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB.. Proc Natl Acad Sci U S A. 107(15):6811-6.
2011
Cheng WWL, McCoy JG, Thompson AN, Nichols CG, Nimigean CM.  2011.  Mechanism for selectivity-inactivation coupling in KcsA potassium channels.. Proc Natl Acad Sci U S A. 108(13):5272-7.
Nimigean CM, Allen TW.  2011.  Origins of ion selectivity in potassium channels from the perspective of channel block.. J Gen Physiol. 137(5):405-13.
2012
McCoy JG, Nimigean CM.  2012.  Structural correlates of selectivity and inactivation in potassium channels.. Biochim Biophys Acta. 1818(2):272-85.
Picollo A, Xu Y, Johner N, Bernèche S, Accardi A.  2012.  Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.. Nat Struct Mol Biol. 19(5):525-31,S1.