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Department of Anesthesiology

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Opioid use disorder and maternal outcomes following cesarean delivery: a multistate analysis, 2007-2014.

TitleOpioid use disorder and maternal outcomes following cesarean delivery: a multistate analysis, 2007-2014.
Publication TypeJournal Article
Year of Publication2020
AuthorsLui B, Aaronson JA, Tangel V, Quincy M, Weinberg R, Abramovitz SE, White RS
JournalJ Comp Eff Res
Date Published2020 Jul 10
ISSN2042-6313
Abstract

To examine the association between opioid use disorder (OUD) and maternal outcomes following cesarean delivery. Retrospective analysis of over 2.4 million discharge records for in-patient cesarean delivery across five states from 2007 to 2014. Primary outcome was in-hospital mortality. Secondary outcomes included length of stay (LOS) and 30- and 90-day readmission rates. OUD patients were 148% more likely than non-OUD patients to die during hospitalization (adjusted odds ratios [aOR]: 2.48, 95% CI: 1.20, 5.10; p < 0.05). OUD was associated with increased odds of 30-day readmission (aOR: 1.46, 95% CI: 1.30, 1.65; p < 0.001) and 90-day readmission (aOR: 1.70, 95% CI: 1.55, 1.88; p < 0.001); LOS was not significantly different. OUD predicts increased in-patient mortality and odds of 30- and 90-day readmission following cesarean delivery.

DOI10.2217/cer-2020-0050
Alternate JournalJ Comp Eff Res
PubMed ID32648478