Department of Anesthesiology

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Measurements of vesicle recycling in central neurons.

TitleMeasurements of vesicle recycling in central neurons.
Publication TypeJournal Article
Year of Publication2001
AuthorsRyan TA, Reuter H
JournalNews Physiol Sci
Volume16
Pagination10-4
Date Published2001 Feb
ISSN0886-1714
KeywordsAnimals, Central Nervous System, Exocytosis, Neurons, Synaptic Vesicles
Abstract

Neurotransmitter-containing vesicles in presynaptic nerve terminals are essential for synaptic transmission. The vesicles undergo a cycle that leads to transmitter release by exocytosis followed by endocytosis and refilling of the vesicles. Here we discuss new optical methods that have helped researchers study this cycle at functional and molecular levels, which is essential for our understanding of the regulation of synaptic transmission.

Alternate JournalNews Physiol. Sci.
PubMed ID11390939