Department of Anesthesiology

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Dynamical basis of intentions and expectations in a simple neuronal network.

TitleDynamical basis of intentions and expectations in a simple neuronal network.
Publication TypeJournal Article
Year of Publication2004
AuthorsProekt A, Brezina V, Weiss KR
JournalProc Natl Acad Sci U S A
Volume101
Issue25
Pagination9447-52
Date Published2004 Jun 22
ISSN0027-8424
KeywordsAnimals, Aplysia, Models, Neurological, Nerve Net, Neurons, Synapses
Abstract

Selection of behavioral responses to external stimuli is strongly influenced by internal states, such as intentions and expectations. These internal states are often attributed to higher-order brain functions. Yet here we show that even in the simple feeding network of Aplysia, external stimuli do not directly specify which motor output is expressed; instead, the motor output is specified by the state of the network at the moment of stimulation. The history-dependence of this network state manifests itself in the same way as do intentions and expectations in the behavior of higher animals. Remarkably, we find that activity-dependent plasticity of a synapse within the network itself, rather than some higher-order network, mediates one important aspect of the change in the network state. Through this mechanism, changes in the network state become an automatic consequence of the generation of behavior. Altogether, our findings suggest that intentions and expectations may emerge within behavior-generating networks themselves from the plasticity of the very processes that generate the behavior.

DOI10.1073/pnas.0402002101
Alternate JournalProc. Natl. Acad. Sci. U.S.A.
PubMed ID15197252
PubMed Central IDPMC438996