Department of Anesthesiology

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Anaemia and red blood cell transfusion in intracranial neurosurgery: a comprehensive review.

TitleAnaemia and red blood cell transfusion in intracranial neurosurgery: a comprehensive review.
Publication TypeJournal Article
Year of Publication2018
AuthorsKisilevsky A, Gelb AW, Bustillo M, Flexman AM
JournalBr J Anaesth
Volume120
Issue5
Pagination988-998
Date Published2018 May
ISSN1471-6771
Abstract

Both anaemia and blood transfusion are associated with poor outcomes in the neurosurgical population. Based on the available literature, the optimal haemoglobin concentration for neurologically injured patients appears to be in the range of 9.0-10.0 g dl, although the individual risks and benefits should be weighed. Several perioperative blood conservation strategies have been used successfully in neurosurgery, including correction of anaemia and coagulopathy, use of antifibrinolytics, and intraoperative cell salvage. Avoidance of non-steroidal anti-inflammatory drugs and starch-containing solutions is recommended given the potential for platelet dysfunction.

DOI10.1016/j.bja.2017.11.108
Alternate JournalBr J Anaesth
PubMed ID29661416

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