Riegelhaupt Lab

Dr. Riegelhaupt

The Riegelhaupt Laboratory is focused on understanding the physiology and pharmacology of tandem pore (K2P) potassium ion channels. K2P channels establish the resting membrane potential of cells throughout the body and modulation of K2P activity shapes cellular excitability. This family of channels plays an important role in a range of human diseases, including cardiac arrhythmia, depression, migraine, and pulmonary hypertension. The laboratory utilizes a combination of electrophysiology, cryo-electron microscopy, and mass spectrometry to define the mechanisms by which anesthetics, lipids, and other pharmacology target K2P channels to modulate their behavior. There are currently no K2P specific drugs in use in clinical practice and we aim to leverage insights into the gating and regulation of these channels to ultimately develop specific and sensitive K2P targeted pharmacology for use in the treatment of human disease.


Dr. Paul Riegelhaupt

Paul Riegelhaupt, MD, PhD — Principal Investigator
Assistant Professor of Anesthesiology

Leila Khajoueinejad, PhD
Postdoctoral Associate

Elena Riel, PhD
Posdoctoral Associate

Gagandeep Singh
Visiting Medical Student


Latrice Goss
Grants & Lab Operations Manager
phone: 646-962-6547
fax: 212-746-4879 

Contact Us

Dept. of Anesthesiology
NewYork-Presbyterian Hospital/Weill Cornell Medicine
525 East 68th Street, Box 124
New York, NY 10065

Office of the Chair
Phone: (212) 746-2962
E-mail:  Office of the Chair, anesthesiology-chair@med.cornell.edu

Residency and Fellowship Education
Direct all inquiries to:
Phone: (212) 746-2941
E-mail: anes-programs@med.cornell.edu
For trainee verification inquiries: anes-verification@med.cornell.edu

Patient Billing Inquiries
Phone: (646) 962-5700