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Author
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Anesthetics, Inhalation
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2021
Speigel IA
,
Hemmings HC
. 2021.
Selective inhibition of gamma aminobutyric acid release from mouse hippocampal interneurone subtypes by the volatile anaesthetic isoflurane.
.
Br J Anaesth. 127(4):587-599.
PubMed
Google Scholar
2020
Wague A
,
Joseph TT
,
Woll KA
,
Bu W
,
Vaidya KA
,
Bhanu NV
,
Garcia BA
,
Nimigean CM
,
Eckenhoff RG
,
Riegelhaupt PM
. 2020.
Mechanistic insights into volatile anesthetic modulation of K2P channels.
.
Elife. 9
PubMed
Google Scholar
2015
Purtell K
,
Gingrich KJ
,
OuYang W
,
Herold KF
,
Hemmings HC
. 2015.
Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.
.
Br J Anaesth. 115(1):112-21.
PubMed
Google Scholar
Mattusch C
,
Kratzer S
,
Buerge M
,
Kreuzer M
,
Engel T
,
Kopp C
,
Biel M
,
Hammelmann V
,
Ying S-W
,
Goldstein PA
et al.
. 2015.
Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments.
.
Anesthesiology. 122(5):1047-59.
PubMed
Google Scholar
2014
Platholi J
,
Herold KF
,
Hemmings HC
,
Halpain S
. 2014.
Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.
.
PLoS One. 9(7):e102978.
PubMed
Google Scholar
Herold KF
,
R Sanford L
,
Lee W
,
Schultz MF
,
Ingólfsson HI
,
Andersen OS
,
Hemmings HC
. 2014.
Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.
.
J Gen Physiol. 144(6):545-60.
PubMed
Google Scholar
2013
Westphalen RI
,
Desai KM
,
Hemmings HC
. 2013.
Presynaptic inhibition of the release of multiple major central nervous system neurotransmitter types by the inhaled anaesthetic isoflurane.
.
Br J Anaesth. 110(4):592-9.
PubMed
Google Scholar
2010
Zhang Y
,
Guzinski M
,
Eger EI
,
Laster MJ
,
Sharma M
,
Harris RA
,
Hemmings HC
. 2010.
Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats.
.
Br J Pharmacol. 159(4):872-8.
PubMed
Google Scholar
2009
Perouansky M
,
Hemmings HC
. 2009.
Between Clotho and Lachesis: how isoflurane seals neuronal fate.
.
Anesthesiology. 110(4):709-11.
PubMed
Google Scholar
Ouyang W
,
Herold KF
,
Hemmings HC
. 2009.
Comparative effects of halogenated inhaled anesthetics on voltage-gated Na+ channel function.
.
Anesthesiology. 110(3):582-90.
PubMed
Google Scholar
Herold KF
,
Nau C
,
Ouyang W
,
Hemmings HC
. 2009.
Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.
.
Anesthesiology. 111(3):591-9.
PubMed
Google Scholar
Ying S-W
,
Werner DF
,
Homanics GE
,
Harrison NL
,
Goldstein PA
. 2009.
Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.
.
Neuropharmacology. 56(2):438-47.
PubMed
Google Scholar
Westphalen RI
,
Gomez RS
,
Hemmings HC
. 2009.
Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane.
.
Br J Anaesth. 102(3):355-60.
PubMed
Google Scholar
Hemmings HC
. 2009.
Sodium channels and the synaptic mechanisms of inhaled anaesthetics.
.
Br J Anaesth. 103(1):61-9.
PubMed
Google Scholar
2008
Hemmings HC
,
Flood P
. 2008.
Galloping in full pursuit of the mechanism of anesthetic immobility.
.
Anesthesiology. 108(6):975-6.
PubMed
Google Scholar
Eger EI
,
Raines DE
,
Shafer SL
,
Hemmings HC
,
Sonner JM
. 2008.
Is a new paradigm needed to explain how inhaled anesthetics produce immobility?
Anesth Analg. 107(3):832-48.
PubMed
Google Scholar
Roepke TK
,
Kontogeorgis A
,
Ovanez C
,
Xu X
,
Young JB
,
Purtell K
,
Goldstein PA
,
Christini DJ
,
Peters NS
,
Akar FG
et al.
. 2008.
Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).
.
FASEB J. 22(10):3648-60.
PubMed
Google Scholar
2007
Snyder GL
,
Galdi S
,
Hendrick JP
,
Hemmings HC
. 2007.
General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.
.
Neuropharmacology. 53(5):619-30.
PubMed
Google Scholar
Ouyang W
,
Jih T-Y
,
Zhang T-T
,
Correa AM
,
Hemmings HC
. 2007.
Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.
.
J Pharmacol Exp Ther. 322(3):1076-83.
PubMed
Google Scholar
Ouyang W
,
Hemmings HC
. 2007.
Isoform-selective effects of isoflurane on voltage-gated Na+ channels.
.
Anesthesiology. 107(1):91-8.
PubMed
Google Scholar
Hemmings HC
. 2007.
Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor.
.
Anesthesiology. 107(5):694-6.
PubMed
Google Scholar
Westphalen RI
,
Krivitski M
,
Amarosa A
,
Guy N
,
Hemmings HC
. 2007.
Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.
.
Br J Pharmacol. 152(6):939-45.
PubMed
Google Scholar
2006
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.
.
J Pharmacol Exp Ther. 316(1):216-23.
PubMed
Google Scholar
Westphalen RI
,
Hemmings HC
. 2006.
Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.
.
J Pharmacol Exp Ther. 316(1):208-15.
PubMed
Google Scholar
2005
Heerdt PM
,
The AHS
,
Markov NP
. 2005.
Anesthetic-induced alteration in expression of myocardial calcium cycling proteins.
.
J Cardiothorac Vasc Anesth. 19(3):340-4.
PubMed
Google Scholar
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