Department of Anesthesiology
Author Title Type [ Year(Asc)]
Filters: Keyword is Structure-Activity Relationship  [Clear All Filters]
2023
Kim J-H, Pandit N, Yoo M, Park THyun, Choi JU, Park CHoon, Jung K-Y, Lee BIl.  2023.  Crystal structure of [1,2,4]triazolo[4,3-b]pyridazine derivatives as BRD4 bromodomain inhibitors and structure-activity relationship study.. Sci Rep. 13(1):10805.
2010
Picollo A, Malvezzi M, Accardi A.  2010.  Proton block of the CLC-5 Cl-/H+ exchanger.. J Gen Physiol. 135(6):653-9.
Savarese JJ, McGilvra JD, Sunaga H, Belmont MR, Van Ornum SG, Savard PM, Heerdt PM.  2010.  Rapid chemical antagonism of neuromuscular blockade by L-cysteine adduction to and inactivation of the olefinic (double-bonded) isoquinolinium diester compounds gantacurium (AV430A), CW 002, and CW 011.. Anesthesiology. 113(1):58-73.
Gradogna A, Babini E, Picollo A, Pusch M.  2010.  A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.. J Gen Physiol. 136(3):311-23.
2008
Bailey LJ, McCoy JG, Phillips GN, Fox BG.  2008.  Structural consequences of effector protein complex formation in a diiron hydroxylase.. Proc Natl Acad Sci U S A. 105(49):19194-8.
2007
McCoy JG, Bitto E, Bingman CA, Wesenberg GE, Bannen RM, Kondrashov DA, Phillips GN.  2007.  Structure and dynamics of UDP-glucose pyrophosphorylase from Arabidopsis thaliana with bound UDP-glucose and UTP.. J Mol Biol. 366(3):830-41.
2006
McCoy JG, Arabshahi A, Bitto E, Bingman CA, Ruzicka FJ, Frey PA, Phillips GN.  2006.  Structure and mechanism of an ADP-glucose phosphorylase from Arabidopsis thaliana.. Biochemistry. 45(10):3154-62.
McCoy JG, Bailey LJ, Bitto E, Bingman CA, Aceti DJ, Fox BG, Phillips GN.  2006.  Structure and mechanism of mouse cysteine dioxygenase.. Proc Natl Acad Sci U S A. 103(9):3084-9.
2004
Liantonio A, Pusch M, Picollo A, Guida P, De Luca A, Pierno S, Fracchiolla G, Loiodice F, Tortorella P, Camerino DConte.  2004.  Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.. J Am Soc Nephrol. 15(1):13-20.
Savarese JJ, Belmont MR, Hashim MA, Mook RA, Boros EE, Samano V, Patel SS, Feldman PL, Schultz J-AI, McNulty M et al..  2004.  Preclinical pharmacology of GW280430A (AV430A) in the rhesus monkey and in the cat: a comparison with mivacurium.. Anesthesiology. 100(4):835-45.
Accardi A, Miller C.  2004.  Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels.. Nature. 427(6977):803-7.
2003
Boros EE, Samano V, Ray JA, Thompson JB, Jung DK, Kaldor I, Koble CS, Martin MT, Styles VL, Mook RA et al..  2003.  Neuromuscular blocking activity and therapeutic potential of mixed-tetrahydroisoquinolinium halofumarates and halosuccinates in rhesus monkeys.. J Med Chem. 46(12):2502-15.
2002
Liantonio A, Accardi A, Carbonara G, Fracchiolla G, Loiodice F, Tortorella P, Traverso S, Guida P, Pierno S, De Luca A et al..  2002.  Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.. Mol Pharmacol. 62(2):265-71.
1994
Fisone G, Cheng SX, Nairn AC, Czernik AJ, Hemmings HC, Höög JO, Bertorello AM, Kaiser R, Bergman T, Jörnvall H.  1994.  Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.. J Biol Chem. 269(12):9368-73.
1990
Hemmings HC, Nairn AC, Elliott JI, Greengard P.  1990.  Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.. J Biol Chem. 265(33):20369-76.
1979
Savarese JJ, Ginsburg S, Braswell L, Kitz RJ.  1979.  Actions at neuromuscular and esteratic cholinoceptive sites of some phenylene diacryloyl bis-cholinium esters.. J Pharmacol Exp Ther. 208(3):436-45.
1975
Savarese JJ, Kitz RJ.  1975.  Does clinical anesthesia need new neuromuscular blocking agents? Anesthesiology. 42(3):236-9.
1971
Ginsburg S, Kitz RJ, Savarese JJ.  1971.  Neuromuscular blocking activity of a new series of quaternary N-substituted choline esters.. Br J Pharmacol. 43(1):107-26.