Department of Anesthesiology
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2014
Rusinova R, Kim DM, Nimigean CM, Andersen OS.  2014.  Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.. Biophys J. 106(5):1070-8.
2013
Posson DJ, Thompson AN, McCoy JG, Nimigean CM.  2013.  Molecular interactions involved in proton-dependent gating in KcsA potassium channels.. J Gen Physiol. 142(6):613-24.
Bhate MP, Wylie BJ, Thompson A, Tian L, Nimigean C, McDermott AE.  2013.  Preparation of uniformly isotope labeled KcsA for solid state NMR: expression, purification, reconstitution into liposomes and functional assay.. Protein Expr Purif. 91(2):119-24.
Posson DJ, McCoy JG, Nimigean CM.  2013.  The voltage-dependent gate in MthK potassium channels is located at the selectivity filter.. Nat Struct Mol Biol. 20(2):159-66.
2012
Lafaille FG, Pessach IM, Zhang S-Y, Ciancanelli MJ, Herman M, Abhyankar A, Ying S-W, Keros S, Goldstein PA, Mostoslavsky G et al..  2012.  Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.. Nature. 491(7426):769-73.
Purtell K, Paroder-Belenitsky M, Reyna-Neyra A, Nicola JP, Koba W, Fine E, Carrasco N, Abbott GW.  2012.  The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake.. FASEB J. 26(8):3252-9.
McCoy JG, Nimigean CM.  2012.  Structural correlates of selectivity and inactivation in potassium channels.. Biochim Biophys Acta. 1818(2):272-85.
Zhu J, Choi W-S, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D et al..  2012.  Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.. Sci Transl Med. 4(125):125ra32.
Zhu J, Choi W-S, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D et al..  2012.  Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.. Sci Transl Med. 4(125):125ra32.
2011
Walaas SIvar, Hemmings HCaroll, Greengard P, Nairn AClark.  2011.  Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases.. Front Neuroanat. 5:50.
Vujosevic S, Smolek MK, Lebow KA, Notaroberto N, Pallikaris A, Casciano M.  2011.  Detection of macular function changes in early (AREDS 2) and intermediate (AREDS 3) age-related macular degeneration.. Ophthalmologica. 225(3):155-60.
Cheng WWL, McCoy JG, Thompson AN, Nichols CG, Nimigean CM.  2011.  Mechanism for selectivity-inactivation coupling in KcsA potassium channels.. Proc Natl Acad Sci U S A. 108(13):5272-7.
Cheng WWL, McCoy JG, Thompson AN, Nichols CG, Nimigean CM.  2011.  Mechanism for selectivity-inactivation coupling in KcsA potassium channels.. Proc Natl Acad Sci U S A. 108(13):5272-7.
Kopman AF, Lien CA, Naguib M.  2011.  Neuromuscular dose-response studies: determining sample size.. Br J Anaesth. 106(2):194-8.
Neumann S, Eliseeva E, McCoy JG, Napolitano G, Giuliani C, Monaco F, Huang W, Gershengorn MC.  2011.  A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor.. J Clin Endocrinol Metab. 96(2):548-54.
Neumann S, Eliseeva E, McCoy JG, Napolitano G, Giuliani C, Monaco F, Huang W, Gershengorn MC.  2011.  A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor.. J Clin Endocrinol Metab. 96(2):548-54.
Banerjee S, Nimigean CM.  2011.  Non-vesicular transfer of membrane proteins from nanoparticles to lipid bilayers.. J Gen Physiol. 137(2):217-23.
Nimigean CM, Allen TW.  2011.  Origins of ion selectivity in potassium channels from the perspective of channel block.. J Gen Physiol. 137(5):405-13.
Fleischut PM, Evans AS, Nugent WC, Faggiani SL, Kerr GE, Lazar EJ.  2011.  Perspective: call to action: it is time for academic institutions to appoint a resident quality and patient safety officer.. Acad Med. 86(7):826-8.
Englund EE, Neumann S, Eliseeva E, McCoy JG, Titus S, Zheng W, Southall N, Shin P, Leister W, Thomas CJ et al..  2011.  The Synthesis and Evaluation of Dihydroquinazolin-4-ones and Quinazolin-4-ones as Thyroid Stimulating Hormone Receptor Agonists.. Medchemcomm. 2(10):1016-1020.
Fleischut PM, Evans AS, Nugent WC, Faggiani SL, Lazar EJ, Liebowitz RS, Forese LL, Kerr GE.  2011.  Ten years after the IOM report: Engaging residents in quality and patient safety by creating a House Staff Quality Council.. Am J Med Qual. 26(2):89-94.
2010
Kopman AF, Lien CA, Naguib M.  2010.  Determining the potency of neuromuscular blockers: are traditional methods flawed? Br J Anaesth. 104(6):705-10.
Glausier JR, Maddox M, Hemmings HC, Nairn AC, Greengard P, Muly EC.  2010.  Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex.. Neuroscience. 167(2):428-38.
Tanabe M, Nimigean CM, Iverson TM.  2010.  Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB.. Proc Natl Acad Sci U S A. 107(15):6811-6.
Naguib M, Kopman AF, Lien CA, Hunter JM, Lopez A, Brull SJ.  2010.  A survey of current management of neuromuscular block in the United States and Europe.. Anesth Analg. 111(1):110-9.