| Title | Gabapentin adjunctive therapy in neuropathic pain states. |
| Publication Type | Journal Article |
| Year of Publication | 1996 |
| Authors | Rosner H, Rubin L, Kestenbaum A |
| Journal | Clin J Pain |
| Volume | 12 |
| Issue | 1 |
| Pagination | 56-8 |
| Date Published | 1996 Mar |
| ISSN | 0749-8047 |
| Keywords | Acetates, Adult, Aged, Amines, Analgesics, Cyclohexanecarboxylic Acids, Facial Pain, Female, gamma-Aminobutyric Acid, Herpesviridae Infections, HIV Infections, Humans, Intervertebral Disc Displacement, Male, Middle Aged, Neuralgia, Pain, Intractable, Peripheral Nervous System Diseases |
| Abstract | OBJECTIVE: This is a report of a trial of the new antiepileptic agent gabapentin in patients with intractable neuropathic pain. DESIGN: A case series of patients with a diagnosis of neuropathic pain whose previous management was inadequate were given oral gabapentin in increasing doses and were followed for a minimum of 2 months, monitored for efficacy and side effects. SETTING: An outpatient pain management center located within a major university medical center. PATIENTS: Convenience sample of patients referred for management of intractable neuropathic pain. INTERVENTIONS: Simplification of existing pharmacologic management, addition of gabapentin, and attempted reduction of opiate analgesic doses. MAIN OUTCOME MEASURES: Patient self-reports and pain scores in successive office visits. RESULTS: Gabapentin provides analgesic activity for patients with neuropathic pain and has the advantage of a low side effect profile and drug toxicity. |
| Alternate Journal | Clin J Pain |
| PubMed ID | 8722736 |