Department of Anesthesiology
Author Title Type [ Year(Desc)]
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2005
Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC.  2005.  Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).. Proc Natl Acad Sci U S A. 102(9):3489-94.
Ying S-W, Goldstein PA.  2005.  Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA(A) receptor chloride channels.. Mol Pain. 1:2.
Ying S-W, Goldstein PA.  2005.  Propofol-block of SK channels in reticular thalamic neurons enhances GABAergic inhibition in relay neurons.. J Neurophysiol. 93(4):1935-48.
2006
Bruening S, Oh E, Hetzenauer A, Escobar-Alvarez S, Westphalen RI, Hemmings HC, Singewald N, Shippenberg T, Toth M.  2006.  The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system.. J Neurochem. 99(3):892-9.
Abbas SY, Ying S-W, Goldstein PA.  2006.  Compartmental distribution of hyperpolarization-activated cyclic-nucleotide-gated channel 2 and hyperpolarization-activated cyclic-nucleotide-gated channel 4 in thalamic reticular and thalamocortical relay neurons.. Neuroscience. 141(4):1811-25.
Ying S-W, Abbas SY, Harrison NL, Goldstein PA.  2006.  Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons.. Eur J Neurosci. 23(2):465-80.
McCoy JG, Bailey LJ, Bitto E, Bingman CA, Aceti DJ, Fox BG, Phillips GN.  2006.  Structure and mechanism of mouse cysteine dioxygenase.. Proc Natl Acad Sci U S A. 103(9):3084-9.
Bitto E, Bingman CA, Wesenberg GE, McCoy JG, Phillips GN.  2006.  Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.. J Biol Chem. 281(29):20521-9.
2007
Ying S-W, Jia F, Abbas SY, Hofmann F, Ludwig A, Goldstein PA.  2007.  Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons.. J Neurosci. 27(32):8719-32.
Mani M, Lee SYoon, Lucast L, Cremona O, Di Paolo G, De Camilli P, Ryan TA.  2007.  The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals.. Neuron. 56(6):1004-18.
Snyder GL, Galdi S, Hendrick JP, Hemmings HC.  2007.  General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.. Neuropharmacology. 53(5):619-30.
Hemmings HC.  2007.  Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor.. Anesthesiology. 107(5):694-6.
Westphalen RI, Krivitski M, Amarosa A, Guy N, Hemmings HC.  2007.  Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.. Br J Pharmacol. 152(6):939-45.
Frederick RO, Bergeman L, Blommel PG, Bailey LJ, McCoy JG, Song J, Meske L, Bingman CA, Riters M, Dillon NA et al..  2007.  Small-scale, semi-automated purification of eukaryotic proteins for structure determination.. J Struct Funct Genomics. 8(4):153-66.
2008
Jia F, Yue M, Chandra D, Homanics GE, Goldstein PA, Harrison NL.  2008.  Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus.. J Pharmacol Exp Ther. 324(3):1127-35.
Eger EI, Raines DE, Shafer SL, Hemmings HC, Sonner JM.  2008.  Is a new paradigm needed to explain how inhaled anesthetics produce immobility? Anesth Analg. 107(3):832-48.
Roepke TK, Kontogeorgis A, Ovanez C, Xu X, Young JB, Purtell K, Goldstein PA, Christini DJ, Peters NS, Akar FG et al..  2008.  Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).. FASEB J. 22(10):3648-60.
Jia F, Yue M, Chandra D, Keramidas A, Goldstein PA, Homanics GE, Harrison NL.  2008.  Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus.. J Neurosci. 28(1):106-15.
Levin EJ, Elsen NL, Seder KD, McCoy JG, Fox BG, Phillips GN.  2008.  X-ray structure of a soluble Rieske-type ferredoxin from Mus musculus.. Acta Crystallogr D Biol Crystallogr. 64(Pt 9):933-40.
2009
Herold KF, Nau C, Ouyang W, Hemmings HC.  2009.  Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.. Anesthesiology. 111(3):591-9.
Ying S-W, Werner DF, Homanics GE, Harrison NL, Goldstein PA.  2009.  Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.. Neuropharmacology. 56(2):438-47.
Jia F, Goldstein PA, Harrison NL.  2009.  The modulation of synaptic GABA(A) receptors in the thalamus by eszopiclone and zolpidem.. J Pharmacol Exp Ther. 328(3):1000-6.
Chatterjee O, Taylor LA, Ahmed S, Nagaraj S, Hall JJ, Finckbeiner SM, Chan PS, Suda N, King JT, Zeeman ML et al..  2009.  Social stress alters expression of large conductance calcium-activated potassium channel subunits in mouse adrenal medulla and pituitary glands.. J Neuroendocrinol. 21(3):167-76.
2010
Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P.  2010.  AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.. EMBO J. 29(16):2813-26.
Roepke TK, Purtell K, King EC, La Perle KMD, Lerner DJ, Abbott GW.  2010.  Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia.. PLoS One. 5(7):e11451.