Author Title Type [ Year(Asc)]
Filters: Keyword is Mutation  [Clear All Filters]
2024
Neelsen LC, Riel EB, Rinné S, Schmid F-R, Jürs BC, Bedoya M, Langer JP, Eymsh B, Kiper AK, Cordeiro S et al..  2024.  Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.. Nat Commun. 15(1):7545.
Thon O, Wang Z, Schmidpeter PAM, Nimigean CM.  2024.  PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK.. Nat Commun. 15(1):8230.
2017
Menny A, Lefebvre SN, Schmidpeter PAm, Drège E, Fourati Z, Delarue M, Edelstein SJ, Nimigean CM, Joseph D, Corringer P-J.  2017.  Identification of a pre-active conformation of a pentameric channel receptor.. Elife. 6
2014
Basilio D, Noack K, Picollo A, Accardi A.  2014.  Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.. Nat Struct Mol Biol. 21(5):456-63.
Corral-Rodríguez MÁngeles, Stuiver M, Abascal-Palacios G, Diercks T, Oyenarte I, Ereño-Orbea J, de Opakua AIbáñez, Blanco FJ, Encinar JAntonio, Spiwok V et al..  2014.  Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.. Biochem J. 464(1):23-34.
Lolicato M, Riegelhaupt PM, Arrigoni C, Clark KA, Minor DL.  2014.  Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.. Neuron. 84(6):1198-212.
2012
McKenna JTimothy, Christie MA, Jeffrey BA, McCoy JG, Lee E, Connolly NP, Ward CP, Strecker RE.  2012.  Chronic ramelteon treatment in a mouse model of Alzheimer's disease.. Arch Ital Biol. 150(1):5-14.
Picollo A, Xu Y, Johner N, Bernèche S, Accardi A.  2012.  Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.. Nat Struct Mol Biol. 19(5):525-31,S1.
2010
Gradogna A, Babini E, Picollo A, Pusch M.  2010.  A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.. J Gen Physiol. 136(3):311-23.
2008
Thompson AN, Posson DJ, Parsa PV, Nimigean CM.  2008.  Molecular mechanism of pH sensing in KcsA potassium channels.. Proc Natl Acad Sci U S A. 105(19):6900-5.
Panaghie G, Purtell K, Tai K-K, Abbott GW.  2008.  Voltage-dependent C-type inactivation in a constitutively open K+ channel.. Biophys J. 95(6):2759-78.
2007
Mani M, Lee SYoon, Lucast L, Cremona O, Di Paolo G, De Camilli P, Ryan TA.  2007.  The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals.. Neuron. 56(6):1004-18.
Nimigean CM, Pagel MD.  2007.  Ligand binding and activation in a prokaryotic cyclic nucleotide-modulated channel.. J Mol Biol. 371(5):1325-37.
Walden M, Accardi A, Wu F, Xu C, Williams C, Miller C.  2007.  Uncoupling and turnover in a Cl-/H+ exchange transporter.. J Gen Physiol. 129(4):317-29.
2005
Accardi A, Walden M, Nguitragool W, Jayaram H, Williams C, Miller C.  2005.  Separate ion pathways in a Cl-/H+ exchanger.. J Gen Physiol. 126(6):563-70.
2004
Crystal RG, Sondhi D, Hackett NR, Kaminsky SM, Worgall S, Stieg P, Souweidane M, Hosain S, Heier L, Ballon D et al..  2004.  Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis.. Hum Gene Ther. 15(11):1131-54.
Accardi A, Kolmakova-Partensky L, Williams C, Miller C.  2004.  Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.. J Gen Physiol. 123(2):109-19.
2003
Accardi A, Pusch M.  2003.  Conformational changes in the pore of CLC-0.. J Gen Physiol. 122(3):277-93.
Schlame M, Kelley RI, Feigenbaum A, Towbin JA, Heerdt PM, Schieble T, Wanders RJA, DiMauro S, Blanck TJJ.  2003.  Phospholipid abnormalities in children with Barth syndrome.. J Am Coll Cardiol. 42(11):1994-9.
2000
Eldin S, Forget AL, Lindenmuth DM, Logan KM, Knight KL.  2000.  Mutations in the N-terminal region of RecA that disrupt the stability of free protein oligomers but not RecA-DNA complexes.. J Mol Biol. 299(1):91-101.
1971
Pakula R, Spencer LR, Goldstein PA.  1971.  Streptococci deficient in genetic transformation.. Can J Microbiol. 17(10):1251-7.