Department of Anesthesiology
Author Title Type [ Year(Desc)]
Filters: Author is Accardi, Alessio  [Clear All Filters]
2002
Iyer R, Iverson TM, Accardi A, Miller C.  2002.  A biological role for prokaryotic ClC chloride channels.. Nature. 419(6908):715-8.
Pusch M, Accardi A, Liantonio A, Guida P, Traverso S, Camerino DConte, Conti F.  2002.  Mechanisms of block of muscle type CLC chloride channels (Review).. Mol Membr Biol. 19(4):285-92.
Liantonio A, Accardi A, Carbonara G, Fracchiolla G, Loiodice F, Tortorella P, Traverso S, Guida P, Pierno S, De Luca A et al..  2002.  Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.. Mol Pharmacol. 62(2):265-71.
2003
Sokolova O, Accardi A, Gutierrez D, Lau A, Rigney M, Grigorieff N.  2003.  Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.. Proc Natl Acad Sci U S A. 100(22):12607-12.
Accardi A, Pusch M.  2003.  Conformational changes in the pore of CLC-0.. J Gen Physiol. 122(3):277-93.
Estévez R, Schroeder BC, Accardi A, Jentsch TJ, Pusch M.  2003.  Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.. Neuron. 38(1):47-59.
2004
Accardi A, Kolmakova-Partensky L, Williams C, Miller C.  2004.  Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.. J Gen Physiol. 123(2):109-19.
Accardi A, Miller C.  2004.  Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels.. Nature. 427(6977):803-7.
2005
Accardi A, Walden M, Nguitragool W, Jayaram H, Williams C, Miller C.  2005.  Separate ion pathways in a Cl-/H+ exchanger.. J Gen Physiol. 126(6):563-70.
2006
Accardi A, Lobet S, Williams C, Miller C, Dutzler R.  2006.  Synergism between halide binding and proton transport in a CLC-type exchanger.. J Mol Biol. 362(4):691-9.
2007
Walden M, Accardi A, Wu F, Xu C, Williams C, Miller C.  2007.  Uncoupling and turnover in a Cl-/H+ exchange transporter.. J Gen Physiol. 129(4):317-29.
2008
Jayaram H, Accardi A, Wu F, Williams C, Miller C.  2008.  Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.. Proc Natl Acad Sci U S A. 105(32):11194-9.
Accardi A.  2008.  To ATP or not to ATP: this is the question.. J Gen Physiol. 131(2):105-8.
2009
Picollo A, Malvezzi M, Houtman JCD, Accardi A.  2009.  Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.. Nat Struct Mol Biol. 16(12):1294-301.
2010
Accardi A, Picollo A.  2010.  CLC channels and transporters: proteins with borderline personalities.. Biochim Biophys Acta. 1798(8):1457-64.
Picollo A, Malvezzi M, Accardi A.  2010.  Proton block of the CLC-5 Cl-/H+ exchanger.. J Gen Physiol. 135(6):653-9.
2011
Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, de Bernabé DBeltrán-V, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ et al..  2011.  A dystroglycan mutation associated with limb-girdle muscular dystrophy.. N Engl J Med. 364(10):939-46.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
2012
Picollo A, Xu Y, Johner N, Bernèche S, Accardi A.  2012.  Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.. Nat Struct Mol Biol. 19(5):525-31,S1.
2013
Malvezzi M, Chalat M, Janjusevic R, Picollo A, Terashima H, Menon AK, Accardi A.  2013.  Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.. Nat Commun. 4:2367.
Terashima H, Picollo A, Accardi A.  2013.  Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels.. Proc Natl Acad Sci U S A. 110(48):19354-9.
2014
Basilio D, Noack K, Picollo A, Accardi A.  2014.  Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.. Nat Struct Mol Biol. 21(5):456-63.
Corral-Rodríguez MÁngeles, Stuiver M, Abascal-Palacios G, Diercks T, Oyenarte I, Ereño-Orbea J, de Opakua AIbáñez, Blanco FJ, Encinar JAntonio, Spiwok V et al..  2014.  Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.. Biochem J. 464(1):23-34.
Accardi A.  2014.  Unveiling the secret lives of glutamate transporters: VGLUTs engage in multiple transport modes.. Neuron. 84(6):1110-2.
2015
Accardi A.  2015.  CELL SIGNALING. Lipids link ion channels and cancer.. Science. 349(6250):789-90.