Department of Anesthesiology
Author Title Type [ Year(Desc)]
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2010
Accardi A, Picollo A.  2010.  CLC channels and transporters: proteins with borderline personalities.. Biochim Biophys Acta. 1798(8):1457-64.
Ariel P, Ryan TA.  2010.  Optical mapping of release properties in synapses.. Front Neural Circuits. 4
Picollo A, Malvezzi M, Accardi A.  2010.  Proton block of the CLC-5 Cl-/H+ exchanger.. J Gen Physiol. 135(6):653-9.
McCoy JG, Marugan JJ, Liu K, Zheng W, Southall N, Huang W, Heilig M, Austin CP.  2010.  Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines as antagonists of the Neuropeptide S Receptor.. ACS Chem Neurosci. 1(8):559-574.
Roepke TK, Purtell K, King EC, La Perle KMD, Lerner DJ, Abbott GW.  2010.  Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia.. PLoS One. 5(7):e11451.
2011
Anand SX, Viles-Gonzalez JF, Mahboobi SK, Heerdt PM.  2011.  Bivalirudin utilization in cardiac surgery: shifting anticoagulation from indirect to direct thrombin inhibition.. Can J Anaesth. 58(3):296-311.
Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, de Bernabé DBeltrán-V, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ et al..  2011.  A dystroglycan mutation associated with limb-girdle muscular dystrophy.. N Engl J Med. 364(10):939-46.
Roepke TK, King EC, Purtell K, Kanda VA, Lerner DJ, Abbott GW.  2011.  Genetic dissection reveals unexpected influence of beta subunits on KCNQ1 K+ channel polarized trafficking in vivo.. FASEB J. 25(2):727-36.
Roepke TK, Kanda VA, Purtell K, King EC, Lerner DJ, Abbott GW.  2011.  KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.. FASEB J. 25(12):4264-73.
Nimigean CM, Allen TW.  2011.  Origins of ion selectivity in potassium channels from the perspective of channel block.. J Gen Physiol. 137(5):405-13.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
Kanda VA, Purtell K, Abbott GW.  2011.  Protein kinase C downregulates I(Ks) by stimulating KCNQ1-KCNE1 potassium channel endocytosis.. Heart Rhythm. 8(10):1641-7.
Englund EE, Neumann S, Eliseeva E, McCoy JG, Titus S, Zheng W, Southall N, Shin P, Leister W, Thomas CJ et al..  2011.  The Synthesis and Evaluation of Dihydroquinazolin-4-ones and Quinazolin-4-ones as Thyroid Stimulating Hormone Receptor Agonists.. Medchemcomm. 2(10):1016-1020.
Rusinova R, Herold KF, R Sanford L, Greathouse DV, Hemmings HC, Andersen OS.  2011.  Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.. J Gen Physiol. 138(2):249-70.
2012
Bailey LJ, Acheson JF, McCoy JG, Elsen NL, Phillips GN, Fox BG.  2012.  Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase.. Biochemistry. 51(6):1101-13.
Lafaille FG, Pessach IM, Zhang S-Y, Ciancanelli MJ, Herman M, Abhyankar A, Ying S-W, Keros S, Goldstein PA, Mostoslavsky G et al..  2012.  Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.. Nature. 491(7426):769-73.
Lafaille FG, Pessach IM, Zhang S-Y, Ciancanelli MJ, Herman M, Abhyankar A, Ying S-W, Keros S, Goldstein PA, Mostoslavsky G et al..  2012.  Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.. Nature. 491(7426):769-73.
Lafaille FG, Pessach IM, Zhang S-Y, Ciancanelli MJ, Herman M, Abhyankar A, Ying S-W, Keros S, Goldstein PA, Mostoslavsky G et al..  2012.  Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.. Nature. 491(7426):769-73.
Ariel P, Hoppa MB, Ryan TA.  2012.  Intrinsic variability in Pv, RRP size, Ca(2+) channel repertoire, and presynaptic potentiation in individual synaptic boutons.. Front Synaptic Neurosci. 4:9.
Purtell K, Paroder-Belenitsky M, Reyna-Neyra A, Nicola JP, Koba W, Fine E, Carrasco N, Abbott GW.  2012.  The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake.. FASEB J. 26(8):3252-9.
Ariel P, Ryan TA.  2012.  New insights into molecular players involved in neurotransmitter release.. Physiology (Bethesda). 27(1):15-24.
Zhu J, Choi W-S, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D et al..  2012.  Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.. Sci Transl Med. 4(125):125ra32.
Picollo A, Xu Y, Johner N, Bernèche S, Accardi A.  2012.  Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.. Nat Struct Mol Biol. 19(5):525-31,S1.
Ying S-W, Kanda VA, Hu Z, Purtell K, King EC, Abbott GW, Goldstein PA.  2012.  Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.. PLoS One. 7(8):e42756.