Department of Anesthesiology
Author Title Type [ Year(Asc)]
Filters: Keyword is Chloride Channels  [Clear All Filters]
2021
Fortea E, Accardi A.  2021.  A quantitative flux assay for the study of reconstituted Cl- channels and transporters.. Methods Enzymol. 652:243-272.
2015
Basilio D, Accardi A.  2015.  A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters.. J Vis Exp. (98)
Picollo A, Malvezzi M, Accardi A.  2015.  TMEM16 proteins: unknown structure and confusing functions.. J Mol Biol. 427(1):94-105.
2014
Basilio D, Noack K, Picollo A, Accardi A.  2014.  Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.. Nat Struct Mol Biol. 21(5):456-63.
2012
Picollo A, Xu Y, Johner N, Bernèche S, Accardi A.  2012.  Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.. Nat Struct Mol Biol. 19(5):525-31,S1.
2010
Accardi A, Picollo A.  2010.  CLC channels and transporters: proteins with borderline personalities.. Biochim Biophys Acta. 1798(8):1457-64.
Zifarelli G, Liantonio A, Gradogna A, Picollo A, Gramegna G, De Bellis M, Murgia AR, Babini E, D Camerino C, Pusch M.  2010.  Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.. Br J Pharmacol. 160(7):1652-61.
Picollo A, Malvezzi M, Accardi A.  2010.  Proton block of the CLC-5 Cl-/H+ exchanger.. J Gen Physiol. 135(6):653-9.
Gradogna A, Babini E, Picollo A, Pusch M.  2010.  A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.. J Gen Physiol. 136(3):311-23.
2009
Picollo A, Malvezzi M, Houtman JCD, Accardi A.  2009.  Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.. Nat Struct Mol Biol. 16(12):1294-301.
2008
Jayaram H, Accardi A, Wu F, Williams C, Miller C.  2008.  Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.. Proc Natl Acad Sci U S A. 105(32):11194-9.
Liantonio A, Picollo A, Carbonara G, Fracchiolla G, Tortorella P, Loiodice F, Laghezza A, Babini E, Zifarelli G, Pusch M et al..  2008.  Molecular switch for CLC-K Cl- channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.. Proc Natl Acad Sci U S A. 105(4):1369-73.
Accardi A.  2008.  To ATP or not to ATP: this is the question.. J Gen Physiol. 131(2):105-8.
2007
Picollo A, Liantonio A, Babini E, Camerino DConte, Pusch M.  2007.  Mechanism of interaction of niflumic acid with heterologously expressed kidney CLC-K chloride channels.. J Membr Biol. 216(2-3):73-82.
Liantonio A, Giannuzzi V, Picollo A, Babini E, Pusch M, D Camerino C.  2007.  Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium.. Br J Pharmacol. 150(2):235-47.
Walden M, Accardi A, Wu F, Xu C, Williams C, Miller C.  2007.  Uncoupling and turnover in a Cl-/H+ exchange transporter.. J Gen Physiol. 129(4):317-29.
2006
Liantonio A, Picollo A, Babini E, Carbonara G, Fracchiolla G, Loiodice F, Tortorella V, Pusch M, Camerino DConte.  2006.  Activation and inhibition of kidney CLC-K chloride channels by fenamates.. Mol Pharmacol. 69(1):165-73.
Pusch M, Zifarelli G, Murgia AR, Picollo A, Babini E.  2006.  Channel or transporter? The CLC saga continues. Exp Physiol. 91(1):149-52.
Accardi A, Lobet S, Williams C, Miller C, Dutzler R.  2006.  Synergism between halide binding and proton transport in a CLC-type exchanger.. J Mol Biol. 362(4):691-9.
2005
Picollo A, Pusch M.  2005.  Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.. Nature. 436(7049):420-3.
Ying S-W, Goldstein PA.  2005.  Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA(A) receptor chloride channels.. Mol Pain. 1:2.
Accardi A, Walden M, Nguitragool W, Jayaram H, Williams C, Miller C.  2005.  Separate ion pathways in a Cl-/H+ exchanger.. J Gen Physiol. 126(6):563-70.
2004
Liantonio A, Pusch M, Picollo A, Guida P, De Luca A, Pierno S, Fracchiolla G, Loiodice F, Tortorella P, Camerino DConte.  2004.  Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.. J Am Soc Nephrol. 15(1):13-20.
Accardi A, Kolmakova-Partensky L, Williams C, Miller C.  2004.  Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.. J Gen Physiol. 123(2):109-19.
Picollo A, Liantonio A, Didonna MPaola, Elia L, Camerino DConte, Pusch M.  2004.  Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.. EMBO Rep. 5(6):584-9.