Department of Anesthesiology
Author Title Type [ Year(Asc)]
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2025
Gao S, Bibineyshvili Y, Safavynia SA, Calderón-Martínez J, Grinspan ZM, Calderon DP.  2025.  Cortical signatures linked to behavior quantitatively track arousal levels.. Proc Natl Acad Sci U S A. 122(19):e2413789122.
2023
Osman V, Speigel I, Patel K, Hemmings HC.  2023.  Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons.. eNeuro. 10(8)
2021
Speigel IA, Hemmings HC.  2021.  Selective inhibition of gamma aminobutyric acid release from mouse hippocampal interneurone subtypes by the volatile anaesthetic isoflurane.. Br J Anaesth. 127(4):587-599.
2020
Wague A, Joseph TT, Woll KA, Bu W, Vaidya KA, Bhanu NV, Garcia BA, Nimigean CM, Eckenhoff RG, Riegelhaupt PM.  2020.  Mechanistic insights into volatile anesthetic modulation of K2P channels.. Elife. 9
2015
Fischer KR, Durrans A, Lee S, Sheng J, Li F, Wong STC, Choi H, Rayes TEl, Ryu S, Troeger J et al..  2015.  Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.. Nature. 527(7579):472-6.
Mattusch C, Kratzer S, Buerge M, Kreuzer M, Engel T, Kopp C, Biel M, Hammelmann V, Ying S-W, Goldstein PA et al..  2015.  Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments.. Anesthesiology. 122(5):1047-59.
2014
Herold KF, R Sanford L, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC.  2014.  Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.. J Gen Physiol. 144(6):545-60.
2013
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.
2012
McKenna JTimothy, Christie MA, Jeffrey BA, McCoy JG, Lee E, Connolly NP, Ward CP, Strecker RE.  2012.  Chronic ramelteon treatment in a mouse model of Alzheimer's disease.. Arch Ital Biol. 150(1):5-14.
Purtell K, Paroder-Belenitsky M, Reyna-Neyra A, Nicola JP, Koba W, Fine E, Carrasco N, Abbott GW.  2012.  The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake.. FASEB J. 26(8):3252-9.
Proekt A, Banavar JR, Maritan A, Pfaff DW.  2012.  Scale invariance in the dynamics of spontaneous behavior.. Proc Natl Acad Sci U S A. 109(26):10564-9.
Zhu J, Choi W-S, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D et al..  2012.  Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.. Sci Transl Med. 4(125):125ra32.
Ying S-W, Kanda VA, Hu Z, Purtell K, King EC, Abbott GW, Goldstein PA.  2012.  Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.. PLoS One. 7(8):e42756.
Hoppa MB, Lana B, Margas W, Dolphin AC, Ryan TA.  2012.  α2δ expression sets presynaptic calcium channel abundance and release probability.. Nature. 486(7401):122-5.
2011
Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, de Bernabé DBeltrán-V, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ et al..  2011.  A dystroglycan mutation associated with limb-girdle muscular dystrophy.. N Engl J Med. 364(10):939-46.
Roepke TK, King EC, Purtell K, Kanda VA, Lerner DJ, Abbott GW.  2011.  Genetic dissection reveals unexpected influence of beta subunits on KCNQ1 K+ channel polarized trafficking in vivo.. FASEB J. 25(2):727-36.
Roepke TK, Kanda VA, Purtell K, King EC, Lerner DJ, Abbott GW.  2011.  KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.. FASEB J. 25(12):4264-73.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
2010
Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P.  2010.  AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.. EMBO J. 29(16):2813-26.
Roepke TK, Purtell K, King EC, La Perle KMD, Lerner DJ, Abbott GW.  2010.  Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia.. PLoS One. 5(7):e11451.
2009
Herold KF, Nau C, Ouyang W, Hemmings HC.  2009.  Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.. Anesthesiology. 111(3):591-9.
Ying S-W, Werner DF, Homanics GE, Harrison NL, Goldstein PA.  2009.  Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.. Neuropharmacology. 56(2):438-47.
Jia F, Goldstein PA, Harrison NL.  2009.  The modulation of synaptic GABA(A) receptors in the thalamus by eszopiclone and zolpidem.. J Pharmacol Exp Ther. 328(3):1000-6.
Chatterjee O, Taylor LA, Ahmed S, Nagaraj S, Hall JJ, Finckbeiner SM, Chan PS, Suda N, King JT, Zeeman ML et al..  2009.  Social stress alters expression of large conductance calcium-activated potassium channel subunits in mouse adrenal medulla and pituitary glands.. J Neuroendocrinol. 21(3):167-76.
2008
Jia F, Yue M, Chandra D, Homanics GE, Goldstein PA, Harrison NL.  2008.  Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus.. J Pharmacol Exp Ther. 324(3):1127-35.