Department of Anesthesiology
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Journal Article
Baumgart JP, Zhou Z-Y, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC.  2015.  Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.. Proc Natl Acad Sci U S A. 112(38):11959-64.
Ouyang W, Wang G, Hemmings HC.  2003.  Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.. Mol Pharmacol. 64(2):373-81.
Osman V, Speigel I, Patel K, Hemmings HC.  2023.  Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons.. eNeuro. 10(8)
Zhang Y, Sharma M, Eger EI, Laster MJ, Hemmings HC, R Harris A.  2008.  Intrathecal veratridine administration increases minimum alveolar concentration in rats.. Anesth Analg. 107(3):875-8.
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.
Snyder GL, Galdi S, Hendrick JP, Hemmings HC.  2007.  General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.. Neuropharmacology. 53(5):619-30.
Pashkov VN, Westphalen RI, Hemmings HC.  2002.  General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals.. Anesthesiology. 97(6):1500-6.
Hemmings HC, Yan W, Westphalen RI, Ryan TA.  2005.  The general anesthetic isoflurane depresses synaptic vesicle exocytosis.. Mol Pharmacol. 67(5):1591-9.
Shahani SK, Lingamaneni R, Hemmings HC.  2002.  General anesthetic actions on norepinephrine, dopamine, and gamma-aminobutyric acid transporters in stably transfected cells.. Anesth Analg. 95(4):893-9,tableofcontents.
Hemmings HC, Flood P.  2008.  Galloping in full pursuit of the mechanism of anesthetic immobility.. Anesthesiology. 108(6):975-6.
Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL.  2005.  Emerging molecular mechanisms of general anesthetic action.. Trends Pharmacol Sci. 26(10):503-10.
Westphalen RI, Hemmings HC.  2003.  Effects of isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals.. Anesthesiology. 98(2):364-72.
Pashkov VN, Hemmings HC.  2002.  The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals.. Anesth Analg. 95(5):1274-81,tableofcontents.
Herold KF, Andersen OS, Hemmings HC.  2017.  Divergent effects of anesthetics on lipid bilayer properties and sodium channel function.. Eur Biophys J. 46(7):617-626.
S Bullock A, Platholi J, Gjyrezi A, Heerdt PM, Tung HYLim, Hemmings HC.  2007.  Differential regulation of protein phosphatase-1(I) by neurabin.. Biochem Biophys Res Commun. 358(1):140-4.
Ouyang W, Hemmings HC.  2005.  Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals.. J Pharmacol Exp Ther. 312(2):801-8.
Hotte M, Thuault S, Lachaise F, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2006.  D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex.. Behav Brain Res. 171(1):127-33.
Ouyang W, Herold KF, Hemmings HC.  2009.  Comparative effects of halogenated inhaled anesthetics on voltage-gated Na+ channel function.. Anesthesiology. 110(3):582-90.
Perouansky M, Hemmings HC.  2009.  Between Clotho and Lachesis: how isoflurane seals neuronal fate.. Anesthesiology. 110(4):709-11.
Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P.  2010.  AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.. EMBO J. 29(16):2813-26.
Platholi J, Heerdt PM, Tung HYLim, Hemmings HC.  2008.  Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma.. J Neurochem. 105(5):2029-38.