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Sunaga, Hiroshi
[Clear All Filters]
2018
Savarese JJ
,
Sunaga H
,
McGilvra JD
,
Belmont MR
,
Murrell MT
,
Jeannotte E
,
Cooke FE
,
Wastila WB
,
Heerdt PM
. 2018.
Preclinical Pharmacology in the Rhesus Monkey of CW 1759-50, a New Ultra-short Acting Nondepolarizing Neuromuscular Blocking Agent, Degraded and Antagonized by L-Cysteine.
.
Anesthesiology. 129(5):970-988.
PubMed
Google Scholar
2016
Heerdt PM
,
Sunaga H
,
Owen JS
,
Murrell MT
,
Malhotra JK
,
Godfrey D
,
Steinkamp M
,
Savard P
,
Savarese JJ
,
Lien CA
. 2016.
Dose-response and Cardiopulmonary Side Effects of the Novel Neuromuscular-blocking Drug CW002 in Man.
.
Anesthesiology. 125(6):1136-1143.
PubMed
Google Scholar
Sunaga H
,
Savarese JJ
,
McGilvra JD
,
Heerdt PM
,
Belmont MR
,
Van Ornum SG
,
Murrell MT
,
Malhotra JK
,
Savard PM
,
Jeannotte E
et al.
. 2016.
Preclinical Pharmacology of CW002: A Nondepolarizing Neuromuscular Blocking Drug of Intermediate Duration, Degraded and Antagonized by l-cysteine-Additional Studies of Safety and Efficacy in the Anesthetized Rhesus Monkey and Cat.
.
Anesthesiology. 125(4):732-743.
PubMed
Google Scholar
2015
Heerdt PM
,
Sunaga H
,
Savarese JJ
. 2015.
Novel neuromuscular blocking drugs and antagonists.
.
Curr Opin Anaesthesiol. 28(4):403-10.
PubMed
Google Scholar
2010
Sunaga H
,
Malhotra JK
,
Yoon E
,
Savarese JJ
,
Heerdt PM
. 2010.
Cysteine reversal of the novel neuromuscular blocking drug CW002 in dogs: pharmacodynamics, acute cardiovascular effects, and preliminary toxicology.
.
Anesthesiology. 112(4):900-9.
PubMed
Google Scholar
Sunaga H
,
Zhang Y
,
Savarese JJ
,
Emala CW
. 2010.
Gantacurium and CW002 do not potentiate muscarinic receptor-mediated airway smooth muscle constriction in guinea pigs.
.
Anesthesiology. 112(4):892-9.
PubMed
Google Scholar
Heerdt PM
,
Malhotra JK
,
Pan BY
,
Sunaga H
,
Savarese JJ
. 2010.
Pharmacodynamics and cardiopulmonary side effects of CW002, a cysteine-reversible neuromuscular blocking drug in dogs.
.
Anesthesiology. 112(4):910-6.
PubMed
Google Scholar
Savarese JJ
,
McGilvra JD
,
Sunaga H
,
Belmont MR
,
Van Ornum SG
,
Savard PM
,
Heerdt PM
. 2010.
Rapid chemical antagonism of neuromuscular blockade by L-cysteine adduction to and inactivation of the olefinic (double-bonded) isoquinolinium diester compounds gantacurium (AV430A), CW 002, and CW 011.
.
Anesthesiology. 113(1):58-73.
PubMed
Google Scholar