Department of Anesthesiology
Journal Article
Ornstein E, Lien CA, Matteo RS, Ostapkovich ND, Diaz J, Wolf KB.  1996.  Pharmacodynamics and pharmacokinetics of cisatracurium in geriatric surgical patients.. Anesthesiology. 84(3):520-5.
Lien CA, Belmont MR, Roth DLWray, Okamoto M, Abalos A, Savarese JJ.  1999.  Pharmacodynamics and the plasma concentration of mivacurium during spontaneous recovery and neostigmine-facilitated recovery.. Anesthesiology. 91(1):119-26.
Kaullen JD, Owen JS, Brouwer KLR, Heerdt PM, Lien CA, Savarese JJ, Schmith VD.  2018.  Pharmacokinetic/Pharmacodynamic Model of CW002, an Investigational Intermediate Neuromuscular Blocking Agent, in Healthy Volunteers.. Anesthesiology. 128(6):1107-1116.
deBros FM, Lai A, Scott R, deBros J, Batson AG, Goudsouzian N, Ali HH, Cosimi AB, Savarese JJ.  1986.  Pharmacokinetics and pharmacodynamics of atracurium during isoflurane anesthesia in normal and anephric patients.. Anesth Analg. 65(7):743-6.
Dresner DL, Basta SJ, Ali HH, Schwartz AF, Embree PB, Wargin WA, Lai AA, Brady KA, Savarese JJ.  1990.  Pharmacokinetics and pharmacodynamics of doxacurium in young and elderly patients during isoflurane anesthesia.. Anesth Analg. 71(5):498-502.
Lien CA, Schmith VD, Embree PB, Belmont MR, Wargin WA, Savarese JJ.  1994.  The pharmacokinetics and pharmacodynamics of the stereoisomers of mivacurium in patients receiving nitrous oxide/opioid/barbiturate anesthesia.. Anesthesiology. 80(6):1296-302.
Lien CA, Schmith VD, Belmont MR, Abalos A, Kisor DF, Savarese JJ.  1996.  Pharmacokinetics of cisatracurium in patients receiving nitrous oxide/opioid/barbiturate anesthesia.. Anesthesiology. 84(2):300-8.
Martyn JA, Matteo RS, Greenblatt DJ, Lebowitz PW, Savarese JJ.  1982.  Pharmacokinetics of d-tubocurarine in patients with thermal injury.. Anesth Analg. 61(3):241-6.
Savarese JJ, Ginsburg S, Lee SM, Kitz RJ.  1973.  The pharmacology of new short-acting nondepolarizing ester neuromuscular blocking agents: clinical implications.. Anesth Analg. 52(6):982-8.
Schlame M, Kelley RI, Feigenbaum A, Towbin JA, Heerdt PM, Schieble T, Wanders RJA, DiMauro S, Blanck TJJ.  2003.  Phospholipid abnormalities in children with Barth syndrome.. J Am Coll Cardiol. 42(11):1994-9.
Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P.  1991.  Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.. Proc Natl Acad Sci U S A. 88(7):2798-801.
Hotte M, Thuault S, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2007.  Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo.. Synapse. 61(1):24-8.
Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.
Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ et al..  1999.  Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.. Nature. 402(6762):669-71.
Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC.  2005.  Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).. Proc Natl Acad Sci U S A. 102(9):3489-94.
Trencheva K, Dhar P, Sonoda T, Lee S, Samuels J, Stein B, Milsom J.  2011.  Physiologic effects of simultaneous carbon dioxide insufflation by laparoscopy and colonoscopy: prospective evaluation.. Surg Endosc. 25(10):3279-85.
Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al..  2014.  Phytochemicals perturb membranes and promiscuously alter protein function.. ACS Chem Biol. 9(8):1788-98.
Girardi NIvascu, Cushing MM.  2023.  Pick your poison: Anemia or transfusion.. Ann Thorac Surg.
Park T, Nimigean CM.  2025.  PIP2 Binding at Allosteric Site Blocks Activation in Human Rod CNG Channels.. bioRxiv.
Thon O, Wang Z, Schmidpeter PAM, Nimigean CM.  2024.  PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK.. Nat Commun. 15(1):8230.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
Redo SF, Dinner MH.  1993.  Placement of central venous catheters by cut-down with electrocardiogram positioning.. Surg Gynecol Obstet. 177(1):49-53.
Romagnoli S, Matta B, Driver BE, Evered L.  2024.  A plea for enhanced monitoring of depth of sedation in patients who are intubated and ventilated.. Crit Care. 28(1):342.
Thalappillil R, White RS, Tam CW.  2020.  POCUS to Guide Fluid Therapy in COVID-19.. J Cardiothorac Vasc Anesth. 34(10):2854-2856.
Nimigean CM.  2020.  Polyamine block of MthK potassium channels.. J Gen Physiol. 152(7)