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Tibbs, Gareth R
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Joyce RL
,
Beyer NP
,
Vasilopoulos G
,
Woll K
,
Hall AC
,
Eckenhoff RG
,
Barman DN
,
J Warren D
,
Tibbs GR
,
Goldstein PA
. 2019.
Alkylphenol inverse agonists of HCN1 gating: H-bond propensity, ring saturation and adduct geometry differentially determine efficacy and potency.
.
Biochem Pharmacol.
PubMed
Google Scholar
Tibbs GR
,
Uprety R
,
J Warren D
,
Beyer NP
,
Joyce RL
,
Ferrer MA
,
Mellado W
,
Wong VSC
,
Goldberg DC
,
Cohen MW
et al.
. 2023.
An anchor-tether 'hindered' HCN1 inhibitor is antihyperalgesic in a rat spared nerve injury neuropathic pain model.
.
Br J Anaesth.
PubMed
Google Scholar
C
Lyashchenko AK
,
Redd KJ
,
Goldstein PA
,
Tibbs GR
. 2014.
cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.
.
PLoS One. 9(7):e101236.
PubMed
Google Scholar
H
Riegelhaupt PM
,
Tibbs GR
,
Goldstein PA
. 2018.
HCN and K Channels in Anesthetic Mechanisms Research.
.
Methods Enzymol. 602:391-416.
PubMed
Google Scholar
Tibbs GR
,
Rowley TJ
,
R Sanford L
,
Herold KF
,
Proekt A
,
Hemmings HC
,
Andersen OS
,
Goldstein PA
,
Flood PD
. 2013.
HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.
.
J Pharmacol Exp Ther. 345(3):363-73.
PubMed
Google Scholar
I
Cacheaux LP
,
Topf N
,
Tibbs GR
,
Schaefer UR
,
Levi R
,
Harrison NL
,
Abbott GW
,
Goldstein PA
. 2005.
Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.
.
J Pharmacol Exp Ther. 315(2):517-25.
PubMed
Google Scholar
P
Ying S-W
,
Tibbs GR
,
Picollo A
,
Abbas SY
,
R Sanford L
,
Accardi A
,
Hofmann F
,
Ludwig A
,
Goldstein PA
. 2011.
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.
.
J Neurosci. 31(28):10412-23.
PubMed
Google Scholar
Joyce RL
,
Tibbs GR
,
J Warren D
,
Costa CJ
,
Aromolaran K
,
R Sanford L
,
Andersen OS
,
Li Z
,
Zhang G
,
Willis DE
et al.
. 2023.
Probucol is anti-hyperalgesic in a mouse peripheral nerve injury model of neuropathic pain.
.
Neurobiol Pain. 14:100141.
PubMed
Google Scholar
Kim ED
,
Wu X
,
Lee S
,
Tibbs GR
,
Cunningham KP
,
Di Zanni E
,
Perez ME
,
Goldstein PA
,
Accardi A
,
H Larsson P
et al.
. 2024.
Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants.
.
Nature.
PubMed
Google Scholar
V
Tibbs GR
,
Posson DJ
,
Goldstein PA
. 2016.
Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain?
Trends Pharmacol Sci. 37(7):522-42.
PubMed
Google Scholar