Department of Anesthesiology
Author Title [ Type(Asc)] Year
Filters: Author is Accardi, Alessio  [Clear All Filters]
Journal Article
Pusch M, Accardi A, Liantonio A, Guida P, Traverso S, Camerino DConte, Conti F.  2002.  Mechanisms of block of muscle type CLC chloride channels (Review).. Mol Membr Biol. 19(4):285-92.
Falzone ME, Malvezzi M, Lee B-C, Accardi A.  2018.  Known structures and unknown mechanisms of TMEM16 scramblases and channels.. J Gen Physiol.
Accardi A, Kolmakova-Partensky L, Williams C, Miller C.  2004.  Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.. J Gen Physiol. 123(2):109-19.
Jayaram H, Accardi A, Wu F, Williams C, Miller C.  2008.  Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.. Proc Natl Acad Sci U S A. 105(32):11194-9.
Feng Z, Di Zanni E, Alvarenga O, Chakraborty S, Rychlik N, Accardi A.  2024.  In or out of the groove? Mechanisms of lipid scrambling by TMEM16 proteins. Cell Calcium. 121:102896.
Lee B-C, Khelashvili G, Falzone M, Menon AK, Weinstein H, Accardi A.  2018.  Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase.. Nat Commun. 9(1):3251.
Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, de Bernabé DBeltrán-V, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ et al..  2011.  A dystroglycan mutation associated with limb-girdle muscular dystrophy.. N Engl J Med. 364(10):939-46.
Khelashvili G, Falzone ME, Cheng X, Lee B-C, Accardi A, Weinstein H.  2019.  Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca-bound nhTMEM16.. Nat Commun. 10(1):4972.
Estévez R, Schroeder BC, Accardi A, Jentsch TJ, Pusch M.  2003.  Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.. Neuron. 38(1):47-59.
Basilio D, Noack K, Picollo A, Accardi A.  2014.  Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.. Nat Struct Mol Biol. 21(5):456-63.
Accardi A, Pusch M.  2003.  Conformational changes in the pore of CLC-0.. J Gen Physiol. 122(3):277-93.
Sokolova O, Accardi A, Gutierrez D, Lau A, Rigney M, Grigorieff N.  2003.  Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.. Proc Natl Acad Sci U S A. 100(22):12607-12.
Accardi A, Picollo A.  2010.  CLC channels and transporters: proteins with borderline personalities.. Biochim Biophys Acta. 1798(8):1457-64.
Accardi A.  2015.  CELL SIGNALING. Lipids link ion channels and cancer.. Science. 349(6250):789-90.
Feng Z, Alvarenga OE, Di Zanni E, Lee S, Khelashvili G, Accardi A.  2026.  Calcium dependent activation of the TMEM16F scramblase and ion channel.. Nat Struct Mol Biol. 33(4):664-676.
Malvezzi M, Chalat M, Janjusevic R, Picollo A, Terashima H, Menon AK, Accardi A.  2013.  Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.. Nat Commun. 4:2367.
Iyer R, Iverson TM, Accardi A, Miller C.  2002.  A biological role for prokaryotic ClC chloride channels.. Nature. 419(6908):715-8.
Picollo A, Malvezzi M, Houtman JCD, Accardi A.  2009.  Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.. Nat Struct Mol Biol. 16(12):1294-301.
Agarwal S, Kim ED, Lee S, Simon A, Accardi A, Nimigean CM.  2025.  Ball-and-chain inactivation of a human large conductance calcium-activated potassium channel.. Nat Commun. 16(1):1769.
Leisle L, Lam K, Dehghani-Ghahnaviyeh S, Fortea E, Galpin JD, Ahern CA, Tajkhorshid E, Accardi A.  2022.  Backbone amides are determinants of Cl- selectivity in CLC ion channels.. Nat Commun. 13(1):7508.
Fortea E, Lee S, Chadda R, Argyros Y, Sandal P, Mahoney-Kruszka R, Ciftci HDidar, Falzone ME, Huysmans G, Robertson JL et al..  2024.  Author Correction: Structural basis of pH-dependent activation in a CLC transporter.. Nat Struct Mol Biol.