Department of Anesthesiology
Journal Article
Zhao W, Zhao S, Zhu T, Ou M, Zhang D, Sun H, Liu J, Chen X, Hemmings HC, Zhou C.  2021.  Isoflurane Suppresses Hippocampal High-frequency Ripples by Differentially Modulating Pyramidal Neurons and Interneurons in Mice.. Anesthesiology.
Platholi J, Herold KF, Hemmings HC, Halpain S.  2014.  Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.. PLoS One. 9(7):e102978.
Zhao W, Zhang M, Liu J, Liang P, Wang R, Hemmings HC, Zhou C.  2019.  Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.. Anesthesiology. 131(1):94-104.
Ying S-W, Werner DF, Homanics GE, Harrison NL, Goldstein PA.  2009.  Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.. Neuropharmacology. 56(2):438-47.
Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC.  2017.  Isoflurane modulates activation and inactivation gating of the prokaryotic Na(+) channel NaChBac.. J Gen Physiol. 149(6):623-638.
Jia F, Yue M, Chandra D, Homanics GE, Goldstein PA, Harrison NL.  2008.  Isoflurane is a potent modulator of extrasynaptic GABA(A) receptors in the thalamus.. J Pharmacol Exp Ther. 324(3):1127-35.
Herold KF, Nau C, Ouyang W, Hemmings HC.  2009.  Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.. Anesthesiology. 111(3):591-9.
Baumgart JP, Zhou Z-Y, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC.  2015.  Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.. Proc Natl Acad Sci U S A. 112(38):11959-64.
Ouyang W, Jih T-Y, Zhang T-T, Correa AM, Hemmings HC.  2007.  Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.. J Pharmacol Exp Ther. 322(3):1076-83.
Torturo CL, Zhou Z-Y, Ryan TA, Hemmings HC.  2019.  Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons.. eNeuro. 6(1)
Ouyang W, Wang G, Hemmings HC.  2003.  Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.. Mol Pharmacol. 64(2):373-81.
Osman V, Speigel I, Patel K, Hemmings HC.  2023.  Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons.. eNeuro. 10(8)
Reed AK, Mercier O, Behr J, Dave K, Dellgren G, Kotecha S, Kukreja J, Landry C, Levvey B, Lyster H et al..  2025.  ISHLT Consensus Statement on the Perioperative use of ECLS in Lung Transplantation: Part I: Preoperative Considerations.. J Heart Lung Transplant.
Martin AKilbourne, Mercier O, Bottiger B, Cypel M, Fessler J, Gomez-De-Antonio D, Levvey B, Lyster H, Nasir B, Sanchez M et al..  2025.  ISHLT consensus statement on the perioperative use of ECLS in lung transplantation: Part III: Postoperative considerations.. J Heart Lung Transplant.
Martin AKilbourne, Mercier O, Fritz AVirginia, Gelzinis TA, Hoetzenecker K, Lindstedt S, Marczin N, Wilkey BJ, Schecter M, Lyster H et al..  2024.  ISHLT consensus statement on the perioperative use of ECLS in lung transplantation: Part II: Intraoperative considerations.. J Heart Lung Transplant.
Marchesi A, Gao X, Adaixo R, Rheinberger J, Stahlberg H, Nimigean C, Scheuring S.  2018.  An iris diaphragm mechanism to gate a cyclic nucleotide-gated ion channel.. Nat Commun. 9(1):3978.
Accardi A, Kolmakova-Partensky L, Williams C, Miller C.  2004.  Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.. J Gen Physiol. 123(2):109-19.
Jayaram H, Accardi A, Wu F, Williams C, Miller C.  2008.  Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.. Proc Natl Acad Sci U S A. 105(32):11194-9.
Neelsen LC, Riel EB, Rinné S, Schmid F-R, Jürs BC, Bedoya M, Langer JP, Eymsh B, Kiper AK, Cordeiro S et al..  2024.  Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.. Nat Commun. 15(1):7545.
Liantonio A, Pusch M, Picollo A, Guida P, De Luca A, Pierno S, Fracchiolla G, Loiodice F, Tortorella P, Camerino DConte.  2004.  Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.. J Am Soc Nephrol. 15(1):13-20.
Twersky RS, Hemmings HC.  2009.  Introduction: 2009 BJA/PGA Supplement: a selection of eight reviews.. Br J Anaesth. 103 Suppl 1:i1-2.
Gari RRSanganna, Tagiltsev G, Pumroy RA, Jiang Y, Blackledge M, Moiseenkova-Bell VY, Scheuring S.  2023.  Intrinsically disordered regions in TRPV2 mediate protein-protein interactions.. Commun Biol. 6(1):966.
Ariel P, Hoppa MB, Ryan TA.  2012.  Intrinsic variability in Pv, RRP size, Ca(2+) channel repertoire, and presynaptic potentiation in individual synaptic boutons.. Front Synaptic Neurosci. 4:9.
Myers LC, Soltesz L, Bosch N, Daly KA, Devis Y, Rucci J, Stevens J, Wunsch H, S Jafarzadeh R, Campbell CI et al..  2024.  Intravenous Opioid Administration During Mechanical Ventilation and Use After Hospital Discharge.. JAMA Netw Open. 7(6):e2417292.
Mehta N, Zocca J, Shaparin N, Snyder M, Singh JR.  2016.  Intravenous Conscious Sedation for Routine Fluoroscopically Guided Lumbar Interventions.. PM R. 8(4):373-9.