Department of Anesthesiology

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Publications

Journal Article
Lien CA, Schmith VD, Embree PB, Belmont MR, Wargin WA, Savarese JJ.  1994.  The pharmacokinetics and pharmacodynamics of the stereoisomers of mivacurium in patients receiving nitrous oxide/opioid/barbiturate anesthesia.. Anesthesiology. 80(6):1296-302.
Lien CA, Schmith VD, Belmont MR, Abalos A, Kisor DF, Savarese JJ.  1996.  Pharmacokinetics of cisatracurium in patients receiving nitrous oxide/opioid/barbiturate anesthesia.. Anesthesiology. 84(2):300-8.
Martyn JA, Matteo RS, Greenblatt DJ, Lebowitz PW, Savarese JJ.  1982.  Pharmacokinetics of d-tubocurarine in patients with thermal injury.. Anesth Analg. 61(3):241-6.
Savarese JJ, Ginsburg S, Lee SM, Kitz RJ.  1973.  The pharmacology of new short-acting nondepolarizing ester neuromuscular blocking agents: clinical implications.. Anesth Analg. 52(6):982-8.
Schlame M, Kelley RI, Feigenbaum A, Towbin JA, Heerdt PM, Schieble T, Wanders RJA, DiMauro S, Blanck TJJ.  2003.  Phospholipid abnormalities in children with Barth syndrome.. J Am Coll Cardiol. 42(11):1994-9.
Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P.  1991.  Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.. Proc Natl Acad Sci U S A. 88(7):2798-801.
Hotte M, Thuault S, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2007.  Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo.. Synapse. 61(1):24-8.
Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.
Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ et al..  1999.  Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.. Nature. 402(6762):669-71.
Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC.  2005.  Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).. Proc Natl Acad Sci U S A. 102(9):3489-94.
Trencheva K, Dhar P, Sonoda T, Lee S, Samuels J, Stein B, Milsom J.  2011.  Physiologic effects of simultaneous carbon dioxide insufflation by laparoscopy and colonoscopy: prospective evaluation.. Surg Endosc. 25(10):3279-85.
Ingólfsson HI, Thakur P, Herold KF, E Hobart A, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K et al..  2014.  Phytochemicals perturb membranes and promiscuously alter protein function.. ACS Chem Biol. 9(8):1788-98.
Ying S-W, Tibbs GR, Picollo A, Abbas SY, R Sanford L, Accardi A, Hofmann F, Ludwig A, Goldstein PA.  2011.  PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.. J Neurosci. 31(28):10412-23.
Redo SF, Dinner MH.  1993.  Placement of central venous catheters by cut-down with electrocardiogram positioning.. Surg Gynecol Obstet. 177(1):49-53.
Hemmings HC, Greengard P.  2010.  Positively active: how local anesthetics work.. Anesthesiology. 113(1):250-2.
Abouarab AA, Leonard JR, Ohmes LB, Lau C, Rong LQ, Ivascu NS, Pryor KO, Munjal M, Crea F, Massetti M et al..  2017.  Posterior Left pericardiotomy for the prevention of postoperative Atrial fibrillation after Cardiac Surgery (PALACS): study protocol for a randomized controlled trial.. Trials. 18(1):593.
Pedoto A, Heerdt PM.  2009.  Postoperative care after pulmonary resection: postanesthesia care unit versus intensive care unit.. Curr Opin Anaesthesiol. 22(1):50-5.
Mack PF, Hass D, Lavyne MH, Snow RB, Lien CA.  2001.  Postoperative narcotic requirement after microscopic lumbar discectomy is not affected by intraoperative ketorolac or bupivacaine.. Spine (Phila Pa 1976). 26(6):658-61.
Naguib M, Lien CA, Aker J, Eliazo R.  2004.  Posttetanic potentiation and fade in the response to tetanic and train-of-four stimulation during succinylcholine-induced block.. Anesth Analg. 98(6):1686-91,tableofcontents.
Savarese JJ, Antonio RP, Ginsburg S.  1975.  Potential clinical uses of short-acting nondepolarizing neuromuscular-blocking agents as predicted from animal experiments.. Anesth Analg. 54(5):669-78.
Lebowitz PW, Ramsey FM, Savarese JJ, Ali HH.  1980.  Potentiation of neuromuscular blockade in man produced by combinations of pancuronium and metocurine or pancuronium and d-tubocurarine.. Anesth Analg. 59(8):604-9.
Amar D, Desiderio DP, Heerdt PM, Kolker AC, Zhang H, Thaler HT.  2008.  Practice patterns in choice of left double-lumen tube size for thoracic surgery.. Anesth Analg. 106(2):379-83,tableofcontents.
Savarese JJ, Sunaga H, McGilvra JD, Belmont MR, Murrell MT, Jeannotte E, Cooke FE, Wastila WB, Heerdt PM.  2018.  Preclinical Pharmacology in the Rhesus Monkey of CW 1759-50, a New Ultra-short Acting Nondepolarizing Neuromuscular Blocking Agent, Degraded and Antagonized by L-Cysteine.. Anesthesiology. 129(5):970-988.
Sunaga H, Savarese JJ, McGilvra JD, Heerdt PM, Belmont MR, Van Ornum SG, Murrell MT, Malhotra JK, Savard PM, Jeannotte E et al..  2016.  Preclinical Pharmacology of CW002: A Nondepolarizing Neuromuscular Blocking Drug of Intermediate Duration, Degraded and Antagonized by l-cysteine-Additional Studies of Safety and Efficacy in the Anesthetized Rhesus Monkey and Cat.. Anesthesiology. 125(4):732-743.
Savarese JJ, Belmont MR, Hashim MA, Mook RA, Boros EE, Samano V, Patel SS, Feldman PL, Schultz J-AI, McNulty M et al..  2004.  Preclinical pharmacology of GW280430A (AV430A) in the rhesus monkey and in the cat: a comparison with mivacurium.. Anesthesiology. 100(4):835-45.