Department of Anesthesiology
Author Title [ Type(Asc)] Year
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Journal Article
Hökfelt T, Foster G, Schultzberg M, Meister B, Schalling M, Goldstein M, Hemmings HC, Ouimet C, Greengard P.  1988.  DARPP-32 as a marker for D-1 dopaminoceptive cells in the rat brain: prenatal development and presence in glial elements (tanycytes) in the basal hypothalamus.. Adv Exp Med Biol. 235:65-82.
Nairn AC, Hemmings HC, Walaas SI, Greengard P.  1988.  DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.. J Neurochem. 50(1):257-62.
Hemmings HC, Greengard P.  1986.  DARPP-32, a dopamine-regulated phosphoprotein.. Prog Brain Res. 69:149-59.
Hemmings HC, Greengard P, Tung HY, Cohen P.  1984.  DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.. Nature. 310(5977):503-5.
Williams KR, Hemmings HC, LoPresti MB, Konigsberg WH, Greengard P.  1986.  DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.. J Biol Chem. 261(4):1890-903.
Hemmings HC, Greengard P.  1986.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution.. J Neurosci. 6(5):1469-81.
Ouimet CC, Miller PE, Hemmings HC, Walaas SI, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization.. J Neurosci. 4(1):111-24.
Hemmings HC, Nairn AC, Aswad DW, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.. J Neurosci. 4(1):99-110.
Hemmings HC, Williams KR, Konigsberg WH, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.. J Biol Chem. 259(23):14486-90.
Hemmings HC, Nairn AC, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.. J Biol Chem. 259(23):14491-7.
Wei L, Schlame M, Downes H, Hemmings HC.  1996.  CHEB, a convulsant barbiturate, evokes calcium-dependent spontaneous glutamate release from rat cerebrocortical synaptosomes.. Neuropharmacology. 35(6):695-701.
Girault JA, Hemmings HC, Zorn SH, Gustafson EL, Greengard P.  1990.  Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.. J Neurochem. 55(5):1772-83.
Hemmings HC, Adamo AI, Hoffman MM.  1995.  Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C.. Anesth Analg. 81(6):1216-22.
Zhang Y, Guzinski M, Eger EI, Laster MJ, Sharma M, Harris RA, Hemmings HC.  2010.  Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats.. Br J Pharmacol. 159(4):872-8.
Hemmings HC, Girault JA, Williams KR, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.. J Biol Chem. 264(13):7726-33.
Ouimet CC, Hemmings HC, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain.. J Neurosci. 9(3):865-75.
Williams KR, Hemmings HC, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus.. J Neurosci. 9(10):3631-7.
Hemmings HC, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.. J Neurosci. 9(3):851-64.
Girault JA, Walaas SI, Hemmings HC, Greengard P.  1990.  ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.. Neuroscience. 37(2):317-25.
Hudson AE, Hemmings HC.  2011.  Are anaesthetics toxic to the brain? Br J Anaesth. 107(1):30-7.
Bruening S, Oh E, Hetzenauer A, Escobar-Alvarez S, Westphalen RI, Hemmings HC, Singewald N, Shippenberg T, Toth M.  2006.  The anxiety-like phenotype of 5-HT receptor null mice is associated with genetic background-specific perturbations in the prefrontal cortex GABA-glutamate system.. J Neurochem. 99(3):892-9.
Lingamaneni R, Krasowski MD, Jenkins A, Truong T, Giunta AL, Blackbeer J, MacIver MB, Harrison NL, Hemmings HC.  2001.  Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.. Anesthesiology. 94(6):1050-7.
Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al..  2013.  Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.. Br J Anaesth. 111(2):143-51.
Purtell K, Gingrich KJ, OuYang W, Herold KF, Hemmings HC.  2015.  Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane.. Br J Anaesth. 115(1):112-21.
Hemmings HC, Adamo AI.  1996.  Activation of endogenous protein kinase C by halothane in synaptosomes.. Anesthesiology. 84(3):652-62.