Department of Anesthesiology
Author Title [ Type(Desc)] Year
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Journal Article
Schlame M, Hemmings HC.  1995.  Inhibition by volatile anesthetics of endogenous glutamate release from synaptosomes by a presynaptic mechanism.. Anesthesiology. 82(6):1406-16.
Ratnakumari L, Hemmings HC.  1998.  Inhibition of presynaptic sodium channels by halothane.. Anesthesiology. 88(4):1043-54.
Lingameneni R, Vysotskaya TN, Duch DS, Hemmings HC.  2000.  Inhibition of voltage-dependent sodium channels by Ro 31-8220, a 'specific' protein kinase C inhibitor.. FEBS Lett. 473(2):265-8.
Strålfors P, Hemmings HC, Greengard P.  1989.  Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical.. Eur J Biochem. 180(1):143-8.
Glausier JR, Maddox M, Hemmings HC, Nairn AC, Greengard P, Muly EC.  2010.  Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex.. Neuroscience. 167(2):428-38.
Schnabel R, Metzger M, Jiang S, Hemmings HC, Greengard P, Braun K.  1997.  Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain.. J Comp Neurol. 388(1):146-68.
King MM, Huang CY, Chock PB, Nairn AC, Hemmings HC, Chan KF, Greengard P.  1984.  Mammalian brain phosphoproteins as substrates for calcineurin.. J Biol Chem. 259(13):8080-3.
Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P.  1995.  Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.. Neuron. 14(2):385-97.
Agnati LF, Fuxe K, Zoli M, Ferraguti F, Benfenati F, Ouimet CC, Walaas SI, Hemmings HC, Goldstein M, Greengard P.  1988.  Morphometrical evidence for a complex organization of tyrosine hydroxylase-, enkephalin- and DARPP-32-like immunoreactive patches and their codistribution at three rostrocaudal levels in the rat neostriatum.. Neuroscience. 27(3):785-97.
Westphalen RI, Gomez RS, Hemmings HC.  2009.  Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane.. Br J Anaesth. 102(3):355-60.
Foster GA, Schultzberg M, Kökfelt T, Goldstein M, Hemmings HC, Ouimet CC, Walaas SI, Greengard P.  1988.  Ontogeny of the dopamine and cyclic adenosine-3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the pre- and postnatal mouse central nervous system.. Int J Dev Neurosci. 6(4):367-86.
Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Greengard P, Czernik AJ.  2001.  Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.. J Neurosci. 21(20):7944-53.
Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P.  1991.  Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.. Proc Natl Acad Sci U S A. 88(7):2798-801.
Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.
Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ et al..  1999.  Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.. Nature. 402(6762):669-71.
Westphalen RI, Desai KM, Hemmings HC.  2013.  Presynaptic inhibition of the release of multiple major central nervous system neurotransmitter types by the inhaled anaesthetic isoflurane.. Br J Anaesth. 110(4):592-9.
Hemmings HC, Nairn AC, Greengard P.  1986.  Protein kinases and phosphoproteins in the nervous system.. Res Publ Assoc Res Nerv Ment Dis. 64:47-69.
Nairn AC, Hemmings HC, Greengard P.  1985.  Protein kinases in the brain.. Annu Rev Biochem. 54:931-76.
Westphalen RI, Krivitski M, Amarosa A, Guy N, Hemmings HC.  2007.  Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.. Br J Pharmacol. 152(6):939-45.
McAvoy T, Allen PB, Obaishi H, Nakanishi H, Takai Y, Greengard P, Nairn AC, Hemmings HC.  1999.  Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.. Biochemistry. 38(39):12943-9.
Hemmings HC, Nairn AC, McGuinness TL, Huganir RL, Greengard P.  1989.  Role of protein phosphorylation in neuronal signal transduction.. FASEB J. 3(5):1583-92.
Hvalby O, Hemmings HC, Paulsen O, Czernik AJ, Nairn AC, Godfraind JM, Jensen V, Raastad M, Storm JF, Andersen P.  1994.  Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.. Proc Natl Acad Sci U S A. 91(11):4761-5.
Chang S, Hemmings HC, Aderem A.  1996.  Stimulus-dependent phosphorylation of MacMARCKS, a protein kinase C substrate, in nerve termini and PC12 cells.. J Biol Chem. 271(2):1174-8.
Hemmings HC, Nairn AC, Elliott JI, Greengard P.  1990.  Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.. J Biol Chem. 265(33):20369-76.
Fu D, Vissavajjhala P, Hemmings HC.  2005.  Volatile anaesthetic effects on phospholipid binding to synaptotagmin 1, a presynaptic Ca2+ sensor.. Br J Anaesth. 95(2):216-21.