Department of Anesthesiology
Author Title [ Type(Desc)] Year
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Journal Article
Schmidpeter PAM, Petroff JT, Khajoueinejad L, Wague A, Frankfater C, Cheng WWL, Nimigean CM, Riegelhaupt PM.  2023.  Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.. Nat Commun. 14(1):1077.
Posson DJ, Thompson AN, McCoy JG, Nimigean CM.  2013.  Molecular interactions involved in proton-dependent gating in KcsA potassium channels.. J Gen Physiol. 142(6):613-24.
Thompson AN, Posson DJ, Parsa PV, Nimigean CM.  2008.  Molecular mechanism of pH sensing in KcsA potassium channels.. Proc Natl Acad Sci U S A. 105(19):6900-5.
Nimigean CM, Miller C.  2002.  Na+ block and permeation in a K+ channel of known structure.. J Gen Physiol. 120(3):323-35.
Banerjee S, Nimigean CM.  2011.  Non-vesicular transfer of membrane proteins from nanoparticles to lipid bilayers.. J Gen Physiol. 137(2):217-23.
Nimigean CM, Allen TW.  2011.  Origins of ion selectivity in potassium channels from the perspective of channel block.. J Gen Physiol. 137(5):405-13.
Lansky S, Betancourt JMichael, Zhang J, Jiang Y, Kim ED, Paknejad N, Nimigean CM, Yuan P, Scheuring S.  2023.  A pentameric TRPV3 channel with a dilated pore.. Nature. 621(7977):206-214.
Thon O, Wang Z, Schmidpeter PAM, Nimigean CM.  2024.  PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK.. Nat Commun. 15(1):8230.
Nimigean CM.  2020.  Polyamine block of MthK potassium channels.. J Gen Physiol. 152(7)
Kim ED, Wu X, Lee S, Tibbs GR, Cunningham KP, Di Zanni E, Perez ME, Goldstein PA, Accardi A, H Larsson P et al..  2024.  Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants.. Nature.
Nimigean CM.  2006.  A radioactive uptake assay to measure ion transport across ion channel-containing liposomes.. Nat Protoc. 1(3):1207-12.
Rangl M, Miyagi A, Kowal J, Stahlberg H, Nimigean CM, Scheuring S.  2016.  Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels.. Nat Commun. 7:12789.
Rusinova R, Kim DM, Nimigean CM, Andersen OS.  2014.  Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.. Biophys J. 106(5):1070-8.
Qian X, Nimigean CM, Niu X, Moss BL, Magleby KL.  2002.  Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels.. J Gen Physiol. 120(6):829-43.
Posson DJ, Rusinova R, Andersen OS, Nimigean CM.  2018.  Stopped-Flow Fluorometric Ion Flux Assay for Ligand-Gated Ion Channel Studies.. Methods Mol Biol. 1684:223-235.
Tanabe M, Nimigean CM, Iverson TM.  2010.  Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB.. Proc Natl Acad Sci U S A. 107(15):6811-6.
McCoy JG, Nimigean CM.  2012.  Structural correlates of selectivity and inactivation in potassium channels.. Biochim Biophys Acta. 1818(2):272-85.
Chiu P-L, Pagel MD, Evans J, Chou H-T, Zeng X, Gipson B, Stahlberg H, Nimigean CM.  2007.  The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MloK1 at 16 A resolution.. Structure. 15(9):1053-64.
Posson DJ, McCoy JG, Nimigean CM.  2013.  The voltage-dependent gate in MthK potassium channels is located at the selectivity filter.. Nat Struct Mol Biol. 20(2):159-66.
Kim DM, Nimigean CM.  2016.  Voltage-Gated Potassium Channels: A Structural Examination of Selectivity and Gating.. Cold Spring Harb Perspect Biol. 8(5)