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Hemmings, Hugh C
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Y
Z
I
Zhang Y
,
Sharma M
,
Eger EI
,
Laster MJ
,
Hemmings HC
,
R Harris A
. 2008.
Intrathecal veratridine administration increases minimum alveolar concentration in rats.
.
Anesth Analg. 107(3):875-8.
PubMed
Google Scholar
Ouyang W
,
Wang G
,
Hemmings HC
. 2003.
Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.
.
Mol Pharmacol. 64(2):373-81.
PubMed
Google Scholar
Torturo CL
,
Zhou Z-Y
,
Ryan TA
,
Hemmings HC
. 2019.
Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons.
.
eNeuro. 6(1)
PubMed
Google Scholar
Ouyang W
,
Jih T-Y
,
Zhang T-T
,
Correa AM
,
Hemmings HC
. 2007.
Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.
.
J Pharmacol Exp Ther. 322(3):1076-83.
PubMed
Google Scholar
Baumgart JP
,
Zhou Z-Y
,
Hara M
,
Cook DC
,
Hoppa MB
,
Ryan TA
,
Hemmings HC
. 2015.
Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.
.
Proc Natl Acad Sci U S A. 112(38):11959-64.
PubMed
Google Scholar
Herold KF
,
Nau C
,
Ouyang W
,
Hemmings HC
. 2009.
Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.
.
Anesthesiology. 111(3):591-9.
PubMed
Google Scholar
Sand RM
,
Gingrich KJ
,
Macharadze T
,
Herold KF
,
Hemmings HC
. 2017.
Isoflurane modulates activation and inactivation gating of the prokaryotic Na(+) channel NaChBac.
.
J Gen Physiol. 149(6):623-638.
PubMed
Google Scholar
Zhao W
,
Zhang M
,
Liu J
,
Liang P
,
Wang R
,
Hemmings HC
,
Zhou C
. 2019.
Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice.
.
Anesthesiology. 131(1):94-104.
PubMed
Google Scholar
Platholi J
,
Herold KF
,
Hemmings HC
,
Halpain S
. 2014.
Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.
.
PLoS One. 9(7):e102978.
PubMed
Google Scholar
Ouyang W
,
Hemmings HC
. 2007.
Isoform-selective effects of isoflurane on voltage-gated Na+ channels.
.
Anesthesiology. 107(1):91-8.
PubMed
Google Scholar
N
Hemmings HC
. 2004.
Neuroprotection by Na+ channel blockade.
.
J Neurosurg Anesthesiol. 16(1):100-1.
PubMed
Google Scholar
Perouansky M
,
Hemmings HC
. 2009.
Neurotoxicity of general anesthetics: cause for concern?
Anesthesiology. 111(6):1365-71.
PubMed
Google Scholar
Eger EI
,
Raines DE
,
Shafer SL
,
Hemmings HC
,
Sonner JM
. 2008.
Is a new paradigm needed to explain how inhaled anesthetics produce immobility?
Anesth Analg. 107(3):832-48.
PubMed
Google Scholar
Hemmings HC
. 2007.
Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor.
.
Anesthesiology. 107(5):694-6.
PubMed
Google Scholar
P
Hotte M
,
Thuault S
,
Dineley KT
,
Hemmings HC
,
Nairn AC
,
Jay TM
. 2007.
Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo.
.
Synapse. 61(1):24-8.
PubMed
Google Scholar
Futter M
,
Uematsu K
,
Bullock SA
,
Kim Y
,
Hemmings HC
,
Nishi A
,
Greengard P
,
Nairn AC
. 2005.
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).
.
Proc Natl Acad Sci U S A. 102(9):3489-94.
PubMed
Google Scholar
Ingólfsson HI
,
Thakur P
,
Herold KF
,
E Hobart A
,
Ramsey NB
,
Periole X
,
de Jong DH
,
Zwama M
,
Yilmaz D
,
Hall K
et al.
. 2014.
Phytochemicals perturb membranes and promiscuously alter protein function.
.
ACS Chem Biol. 9(8):1788-98.
PubMed
Google Scholar
Hemmings HC
,
Greengard P
. 2010.
Positively active: how local anesthetics work.
.
Anesthesiology. 113(1):250-2.
PubMed
Google Scholar
Zhang TT
,
Platholi J
,
Heerdt PM
,
Hemmings HC
,
Tung HYL
. 2008.
Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation.
.
Metab Brain Dis. 23(1):95-104.
PubMed
Google Scholar
R
Morrow PW
,
Tung HYLim
,
Hemmings HC
. 2004.
Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells.
.
Biochem Biophys Res Commun. 323(2):645-51.
PubMed
Google Scholar
Westphalen RI
,
Yu J
,
Krivitski M
,
Jih T-Y
,
Hemmings HC
. 2010.
Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS.
.
J Neurochem. 113(6):1611-20.
PubMed
Google Scholar
Westphalen RI
,
Kwak N-B
,
Daniels K
,
Hemmings HC
. 2011.
Regional differences in the effects of isoflurane on neurotransmitter release.
.
Neuropharmacology. 61(4):699-706.
PubMed
Google Scholar
Platholi J
,
Federman A
,
Detert JA
,
Heerdt P
,
Hemmings HC
. 2014.
Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.
.
J Biol Chem. 289(34):23893-900.
PubMed
Google Scholar
Nguyen C
,
Nishi A
,
Kansy JW
,
Fernandez J
,
Hayashi K
,
Gillardon F
,
Hemmings HC
,
Nairn AC
,
Bibb JA
. 2007.
Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.
.
J Biol Chem. 282(22):16511-20.
PubMed
Google Scholar
Riegelhaupt PM
,
Hemmings HC
,
Goldstein PA
. 2016.
Relevance of Clinical Relevance.
.
Anesthesiology. 125(4):821-2.
PubMed
Google Scholar
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