Department of Anesthesiology
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2014
Platholi J, Federman A, Detert JA, Heerdt P, Hemmings HC.  2014.  Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.. J Biol Chem. 289(34):23893-900.
Huang V, Hemmings HC, Crews D.  2014.  Sociosexual investigation in sexually experienced, hormonally manipulated male leopard geckos: relation with phosphorylated DARPP-32 in dopaminergic pathways.. J Exp Zool A Ecol Genet Physiol. 321(10):595-602.
Lolicato M, Riegelhaupt PM, Arrigoni C, Clark KA, Minor DL.  2014.  Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.. Neuron. 84(6):1198-212.
Accardi A.  2014.  Unveiling the secret lives of glutamate transporters: VGLUTs engage in multiple transport modes.. Neuron. 84(6):1110-2.
Herold KF, R Sanford L, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC.  2014.  Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.. J Gen Physiol. 144(6):545-60.
2013
Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al..  2013.  Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.. Br J Anaesth. 111(2):143-51.
Kim SHyun, Ryan TA.  2013.  Balance of calcineurin Aα and CDK5 activities sets release probability at nerve terminals.. J Neurosci. 33(21):8937-50.
McCoy JG, Christie MA, Kim Y, Brennan R, Poeta DL, McCarley RW, Strecker RE.  2013.  Chronic sleep restriction impairs spatial memory in rats.. Neuroreport. 24(2):91-5.
Hanbury DB, Edens KD, M Fontenot B, Greer TF, McCoy JG, Watson SL.  2013.  Handedness and lateralised tympanic membrane temperature in relation to approach-avoidance behaviour in Garnett's bushbaby (Otolemur garnettii).. Laterality. 18(1):120-33.
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.
Westphalen RI, Desai KM, Hemmings HC.  2013.  Presynaptic inhibition of the release of multiple major central nervous system neurotransmitter types by the inhaled anaesthetic isoflurane.. Br J Anaesth. 110(4):592-9.
2012
Pan P-Y, Ryan TA.  2012.  Calbindin controls release probability in ventral tegmental area dopamine neurons.. Nat Neurosci. 15(6):813-5.
McKenna JTimothy, Christie MA, Jeffrey BA, McCoy JG, Lee E, Connolly NP, Ward CP, Strecker RE.  2012.  Chronic ramelteon treatment in a mouse model of Alzheimer's disease.. Arch Ital Biol. 150(1):5-14.
Purtell K, Paroder-Belenitsky M, Reyna-Neyra A, Nicola JP, Koba W, Fine E, Carrasco N, Abbott GW.  2012.  The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake.. FASEB J. 26(8):3252-9.
Ariel P, Ryan TA.  2012.  New insights into molecular players involved in neurotransmitter release.. Physiology (Bethesda). 27(1):15-24.
Proekt A, Banavar JR, Maritan A, Pfaff DW.  2012.  Scale invariance in the dynamics of spontaneous behavior.. Proc Natl Acad Sci U S A. 109(26):10564-9.
McCoy JG, Nimigean CM.  2012.  Structural correlates of selectivity and inactivation in potassium channels.. Biochim Biophys Acta. 1818(2):272-85.
Zhu J, Choi W-S, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D et al..  2012.  Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.. Sci Transl Med. 4(125):125ra32.
Ying S-W, Kanda VA, Hu Z, Purtell K, King EC, Abbott GW, Goldstein PA.  2012.  Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.. PLoS One. 7(8):e42756.
Heerdt PM, Kant R, Hu Z, Kanda VA, Christini DJ, Malhotra JK, Abbott GW.  2012.  Transcriptomic analysis reveals atrial KCNE1 down-regulation following lung lobectomy.. J Mol Cell Cardiol. 53(3):350-3.
Hoppa MB, Lana B, Margas W, Dolphin AC, Ryan TA.  2012.  α2δ expression sets presynaptic calcium channel abundance and release probability.. Nature. 486(7401):122-5.
2011
Hudson AE, Hemmings HC.  2011.  Are anaesthetics toxic to the brain? Br J Anaesth. 107(1):30-7.
Hara Y, Balci-Hayta B, Yoshida-Moriguchi T, Kanagawa M, de Bernabé DBeltrán-V, Gündeşli H, Willer T, Satz JS, Crawford RW, Burden SJ et al..  2011.  A dystroglycan mutation associated with limb-girdle muscular dystrophy.. N Engl J Med. 364(10):939-46.
Roepke TK, King EC, Purtell K, Kanda VA, Lerner DJ, Abbott GW.  2011.  Genetic dissection reveals unexpected influence of beta subunits on KCNQ1 K+ channel polarized trafficking in vivo.. FASEB J. 25(2):727-36.
Roepke TK, Kanda VA, Purtell K, King EC, Lerner DJ, Abbott GW.  2011.  KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.. FASEB J. 25(12):4264-73.