Department of Anesthesiology
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2001
Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Greengard P, Czernik AJ.  2001.  Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.. J Neurosci. 21(20):7944-53.
Chi P, Greengard P, Ryan TA.  2001.  Synapsin dispersion and reclustering during synaptic activity.. Nat Neurosci. 4(12):1187-93.
2000
Nimigean CM, Magleby KL.  2000.  Functional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism.. J Gen Physiol. 115(6):719-36.
Sankaranarayanan S, Ryan TA.  2000.  Real-time measurements of vesicle-SNARE recycling in synapses of the central nervous system.. Nat Cell Biol. 2(4):197-204.
1999
Nimigean CM, Magleby KL.  1999.  The beta subunit increases the Ca2+ sensitivity of large conductance Ca2+-activated potassium channels by retaining the gating in the bursting states.. J Gen Physiol. 113(3):425-40.
Moss BL, Silberberg SD, Nimigean CM, Magleby KL.  1999.  Ca2+-dependent gating mechanisms for dSlo, a large-conductance Ca2+-activated K+ (BK) channel.. Biophys J. 76(6):3099-117.
Ryan TA.  1999.  Inhibitors of myosin light chain kinase block synaptic vesicle pool mobilization during action potential firing.. J Neurosci. 19(4):1317-23.
1996
Ratnakumari L, Hemmings HC.  1996.  Inhibition by propofol of [3H]-batrachotoxinin-A 20-alpha-benzoate binding to voltage-dependent sodium channels in rat cortical synaptosomes.. Br J Pharmacol. 119(7):1498-504.
1995
Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P.  1995.  Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.. Neuron. 14(2):385-97.
1994
Hemmings HC, Adamo AI.  1994.  Effects of halothane and propofol on purified brain protein kinase C activation.. Anesthesiology. 81(1):147-55.
Fisone G, Cheng SX, Nairn AC, Czernik AJ, Hemmings HC, Höög JO, Bertorello AM, Kaiser R, Bergman T, Jörnvall H.  1994.  Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.. J Biol Chem. 269(12):9368-73.
1991
Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P.  1991.  Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.. Proc Natl Acad Sci U S A. 88(7):2798-801.
1990
Hemmings HC, Nairn AC, Elliott JI, Greengard P.  1990.  Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.. J Biol Chem. 265(33):20369-76.
1989
Hemmings HC, Girault JA, Williams KR, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.. J Biol Chem. 264(13):7726-33.
Meister B, Fryckstedt J, Schalling M, Cortés R, Hökfelt T, Aperia A, Hemmings HC, Nairn AC, Ehrlich M, Greengard P.  1989.  Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.. Proc Natl Acad Sci U S A. 86(20):8068-72.
Millard PJ, Ryan TA, Webb WW, Fewtrell C.  1989.  Immunoglobulin E receptor cross-linking induces oscillations in intracellular free ionized calcium in individual tumor mast cells.. J Biol Chem. 264(33):19730-9.
Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.
1987
Khojasteh A, Evans W, Reynolds RD, Thomas G, Savarese JJ.  1987.  Controlled-release oral morphine sulfate in the treatment of cancer pain with pharmacokinetic correlation.. J Clin Oncol. 5(6):956-61.
1986
deBros FM, Lai A, Scott R, deBros J, Batson AG, Goudsouzian N, Ali HH, Cosimi AB, Savarese JJ.  1986.  Pharmacokinetics and pharmacodynamics of atracurium during isoflurane anesthesia in normal and anephric patients.. Anesth Analg. 65(7):743-6.
Savarese JJ, Goldenheim PD, Thomas GB, Kaiko RF.  1986.  Steady-state pharmacokinetics of controlled release oral morphine sulphate in healthy subjects.. Clin Pharmacokinet. 11(6):505-10.
1984
Hemmings HC, Nairn AC, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.. J Biol Chem. 259(23):14491-7.
King MM, Huang CY, Chock PB, Nairn AC, Hemmings HC, Chan KF, Greengard P.  1984.  Mammalian brain phosphoproteins as substrates for calcineurin.. J Biol Chem. 259(13):8080-3.
1982
Martyn JA, Matteo RS, Greenblatt DJ, Lebowitz PW, Savarese JJ.  1982.  Pharmacokinetics of d-tubocurarine in patients with thermal injury.. Anesth Analg. 61(3):241-6.
1979
Savarese JJ, Berkowitz BA.  1979.  beta-Adrenergic receptor decrease in diabetic rat hearts.. Life Sci. 25(24-25):2075-8.