Department of Anesthesiology

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Publications

Author Title [ Type(Desc)] Year
Filters: Keyword is Chloride Channels  [Clear All Filters]
Journal Article
Liantonio A, Picollo A, Babini E, Carbonara G, Fracchiolla G, Loiodice F, Tortorella V, Pusch M, Camerino DConte.  2006.  Activation and inhibition of kidney CLC-K chloride channels by fenamates.. Mol Pharmacol. 69(1):165-73.
Picollo A, Malvezzi M, Houtman JCD, Accardi A.  2009.  Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.. Nat Struct Mol Biol. 16(12):1294-301.
Iyer R, Iverson TM, Accardi A, Miller C.  2002.  A biological role for prokaryotic ClC chloride channels.. Nature. 419(6908):715-8.
Pusch M, Zifarelli G, Murgia AR, Picollo A, Babini E.  2006.  Channel or transporter? The CLC saga continues. Exp Physiol. 91(1):149-52.
Picollo A, Pusch M.  2005.  Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.. Nature. 436(7049):420-3.
Accardi A, Picollo A.  2010.  CLC channels and transporters: proteins with borderline personalities.. Biochim Biophys Acta. 1798(8):1457-64.
Accardi A, Pusch M.  2003.  Conformational changes in the pore of CLC-0.. J Gen Physiol. 122(3):277-93.
Basilio D, Noack K, Picollo A, Accardi A.  2014.  Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.. Nat Struct Mol Biol. 21(5):456-63.
Estévez R, Schroeder BC, Accardi A, Jentsch TJ, Pusch M.  2003.  Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.. Neuron. 38(1):47-59.
Zifarelli G, Liantonio A, Gradogna A, Picollo A, Gramegna G, De Bellis M, Murgia AR, Babini E, D Camerino C, Pusch M.  2010.  Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.. Br J Pharmacol. 160(7):1652-61.
Liantonio A, Pusch M, Picollo A, Guida P, De Luca A, Pierno S, Fracchiolla G, Loiodice F, Tortorella P, Camerino DConte.  2004.  Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.. J Am Soc Nephrol. 15(1):13-20.
Jayaram H, Accardi A, Wu F, Williams C, Miller C.  2008.  Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.. Proc Natl Acad Sci U S A. 105(32):11194-9.
Accardi A, Kolmakova-Partensky L, Williams C, Miller C.  2004.  Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.. J Gen Physiol. 123(2):109-19.
Picollo A, Liantonio A, Babini E, Camerino DConte, Pusch M.  2007.  Mechanism of interaction of niflumic acid with heterologously expressed kidney CLC-K chloride channels.. J Membr Biol. 216(2-3):73-82.
Pusch M, Accardi A, Liantonio A, Guida P, Traverso S, Camerino DConte, Conti F.  2002.  Mechanisms of block of muscle type CLC chloride channels (Review).. Mol Membr Biol. 19(4):285-92.
Picollo A, Liantonio A, Didonna MPaola, Elia L, Camerino DConte, Pusch M.  2004.  Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.. EMBO Rep. 5(6):584-9.
Liantonio A, Accardi A, Carbonara G, Fracchiolla G, Loiodice F, Tortorella P, Traverso S, Guida P, Pierno S, De Luca A et al..  2002.  Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.. Mol Pharmacol. 62(2):265-71.
Liantonio A, Picollo A, Carbonara G, Fracchiolla G, Tortorella P, Loiodice F, Laghezza A, Babini E, Zifarelli G, Pusch M et al..  2008.  Molecular switch for CLC-K Cl- channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.. Proc Natl Acad Sci U S A. 105(4):1369-73.
Liantonio A, Giannuzzi V, Picollo A, Babini E, Pusch M, D Camerino C.  2007.  Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium.. Br J Pharmacol. 150(2):235-47.
Ying S-W, Goldstein PA.  2005.  Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA(A) receptor chloride channels.. Mol Pain. 1:2.
Basilio D, Accardi A.  2015.  A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters.. J Vis Exp. (98)
Picollo A, Malvezzi M, Accardi A.  2010.  Proton block of the CLC-5 Cl-/H+ exchanger.. J Gen Physiol. 135(6):653-9.
Gradogna A, Babini E, Picollo A, Pusch M.  2010.  A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.. J Gen Physiol. 136(3):311-23.
Accardi A, Miller C.  2004.  Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels.. Nature. 427(6977):803-7.
Accardi A, Walden M, Nguitragool W, Jayaram H, Williams C, Miller C.  2005.  Separate ion pathways in a Cl-/H+ exchanger.. J Gen Physiol. 126(6):563-70.