Department of Anesthesiology
Author Title Type [ Year(Desc)]
Filters: Keyword is Ligands  [Clear All Filters]
2005
Hemmings HC, Akabas MH, Goldstein PA, Trudell JR, Orser BA, Harrison NL.  2005.  Emerging molecular mechanisms of general anesthetic action.. Trends Pharmacol Sci. 26(10):503-10.
2006
McCoy JG, Bailey LJ, Bitto E, Bingman CA, Aceti DJ, Fox BG, Phillips GN.  2006.  Structure and mechanism of mouse cysteine dioxygenase.. Proc Natl Acad Sci U S A. 103(9):3084-9.
2007
Nimigean CM, Pagel MD.  2007.  Ligand binding and activation in a prokaryotic cyclic nucleotide-modulated channel.. J Mol Biol. 371(5):1325-37.
2008
Liantonio A, Picollo A, Carbonara G, Fracchiolla G, Tortorella P, Loiodice F, Laghezza A, Babini E, Zifarelli G, Pusch M et al..  2008.  Molecular switch for CLC-K Cl- channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.. Proc Natl Acad Sci U S A. 105(4):1369-73.
Eger EI, Raines DE, Shafer SL, Hemmings HC, Sonner JM.  2008.  Is a new paradigm needed to explain how inhaled anesthetics produce immobility? Anesth Analg. 107(3):832-48.
2009
McCoy JG, Johnson HD, Singh S, Bingman CA, Lei I-K, Thorson JS, Phillips GN.  2009.  Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway.. Proteins. 74(1):50-60.
2012
Bailey LJ, Acheson JF, McCoy JG, Elsen NL, Phillips GN, Fox BG.  2012.  Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase.. Biochemistry. 51(6):1101-13.
2014
Kowal J, Chami M, Baumgartner P, Arheit M, Chiu P-L, Rangl M, Scheuring S, Schröder GF, Nimigean CM, Stahlberg H.  2014.  Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.. Nat Commun. 5:3106.
2022
Gao X, Schmidpeter PAM, Berka V, Durham RJ, Fan C, Jayaraman V, Nimigean CM.  2022.  Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.. Nat Commun. 13(1):6919.