Department of Anesthesiology
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Filters: Keyword is Anesthetics, Inhalation  [Clear All Filters]
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Lingamaneni R, Birch ML, Hemmings HC.  2001.  Widespread inhibition of sodium channel-dependent glutamate release from isolated nerve terminals by isoflurane and propofol.. Anesthesiology. 95(6):1460-6.
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Herold KF, R Sanford L, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC.  2014.  Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.. J Gen Physiol. 144(6):545-60.
Westphalen RI, Hemmings HC.  2006.  Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release.. J Pharmacol Exp Ther. 316(1):208-15.
Westphalen RI, Hemmings HC.  2006.  Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release.. J Pharmacol Exp Ther. 316(1):216-23.
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Roepke TK, Kontogeorgis A, Ovanez C, Xu X, Young JB, Purtell K, Goldstein PA, Christini DJ, Peters NS, Akar FG et al..  2008.  Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).. FASEB J. 22(10):3648-60.
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Hemmings HC.  2009.  Sodium channels and the synaptic mechanisms of inhaled anaesthetics.. Br J Anaesth. 103(1):61-9.
Speigel IA, Hemmings HC.  2021.  Selective inhibition of gamma aminobutyric acid release from mouse hippocampal interneurone subtypes by the volatile anaesthetic isoflurane.. Br J Anaesth. 127(4):587-599.
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Westphalen RI, Krivitski M, Amarosa A, Guy N, Hemmings HC.  2007.  Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1.. Br J Pharmacol. 152(6):939-45.
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Westphalen RI, Desai KM, Hemmings HC.  2013.  Presynaptic inhibition of the release of multiple major central nervous system neurotransmitter types by the inhaled anaesthetic isoflurane.. Br J Anaesth. 110(4):592-9.
Lien CA, Schmith VD, Belmont MR, Abalos A, Kisor DF, Savarese JJ.  1996.  Pharmacokinetics of cisatracurium in patients receiving nitrous oxide/opioid/barbiturate anesthesia.. Anesthesiology. 84(2):300-8.
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Hemmings HC.  2007.  Noble meets nouveau: a shared anesthetic binding site for xenon and isoflurane on a glutamate receptor.. Anesthesiology. 107(5):694-6.
Westphalen RI, Gomez RS, Hemmings HC.  2009.  Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane.. Br J Anaesth. 102(3):355-60.
Eger EI, Raines DE, Shafer SL, Hemmings HC, Sonner JM.  2008.  Is a new paradigm needed to explain how inhaled anesthetics produce immobility? Anesth Analg. 107(3):832-48.
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Wague A, Joseph TT, Woll KA, Bu W, Vaidya KA, Bhanu NV, Garcia BA, Nimigean CM, Eckenhoff RG, Riegelhaupt PM.  2020.  Mechanistic insights into volatile anesthetic modulation of K2P channels.. Elife. 9
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Ouyang W, Hemmings HC.  2007.  Isoform-selective effects of isoflurane on voltage-gated Na+ channels.. Anesthesiology. 107(1):91-8.
Platholi J, Herold KF, Hemmings HC, Halpain S.  2014.  Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism.. PLoS One. 9(7):e102978.
Ying S-W, Werner DF, Homanics GE, Harrison NL, Goldstein PA.  2009.  Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.. Neuropharmacology. 56(2):438-47.
Herold KF, Nau C, Ouyang W, Hemmings HC.  2009.  Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8.. Anesthesiology. 111(3):591-9.
Ouyang W, Jih T-Y, Zhang T-T, Correa AM, Hemmings HC.  2007.  Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.. J Pharmacol Exp Ther. 322(3):1076-83.
Ouyang W, Wang G, Hemmings HC.  2003.  Isoflurane and propofol inhibit voltage-gated sodium channels in isolated rat neurohypophysial nerve terminals.. Mol Pharmacol. 64(2):373-81.
Ratnakumari L, Hemmings HC.  1998.  Inhibition of presynaptic sodium channels by halothane.. Anesthesiology. 88(4):1043-54.
Mattusch C, Kratzer S, Buerge M, Kreuzer M, Engel T, Kopp C, Biel M, Hammelmann V, Ying S-W, Goldstein PA et al..  2015.  Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments.. Anesthesiology. 122(5):1047-59.
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Snyder GL, Galdi S, Hendrick JP, Hemmings HC.  2007.  General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.. Neuropharmacology. 53(5):619-30.
Hemmings HC, Yan W, Westphalen RI, Ryan TA.  2005.  The general anesthetic isoflurane depresses synaptic vesicle exocytosis.. Mol Pharmacol. 67(5):1591-9.
Hemmings HC, Flood P.  2008.  Galloping in full pursuit of the mechanism of anesthetic immobility.. Anesthesiology. 108(6):975-6.